Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 6/20 | 0.77 |
| ▸ | MAPT | P10636 | 3/20 | 0.77 |
| ▸ | BACE1 | P56817 | 3/20 | 0.71 |
| ▸ | TTR | P02766 | 1/20 | 0.69 |
| ▸ | MAOB | P27338 | 2/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.62 |
| ▸ | TYR | P14679 | 1/20 | 0.61 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.60 |
| ▸ | XDH | P47989 | 1/20 | 0.60 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.58 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.57 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.57 |
| ▸ | RELA | Q04206 | 2/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.57 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.56 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5360748 | 1.00 | APP (0.77) | APPMAPTBACE1TTRMAOB | |
| SCHEMBL13191839 | 0.87 | APP (1.00) | APPMAPTBACE1TTRNFE2L2 | |
| SCHEMBL1603801 | 0.87 | APP (0.87) | APPMAPTBACE1TTRMAOB | |
| SCHEMBL1603799 | 0.87 | APP (0.87) | APPMAPTBACE1TTRMAOB | |
| SCHEMBL29373798 | 0.87 | APP (1.00) | APPMAPTBACE1TTRNFE2L2 | |
| SCHEMBL1607405 | 0.87 | APP (1.00) | APPMAPTBACE1TTRNFE2L2 | |
| SCHEMBL10167885 | 0.87 | APP (1.00) | APPMAPTBACE1TTRNFE2L2 | |
| SCHEMBL5315843 | 0.85 | TTR (0.80) | APPMAPTTTRMAOBNFE2L2 | |
| SCHEMBL9616786 | 0.85 | TTR (0.80) | APPMAPTTTRMAOBNFE2L2 | |
| SCHEMBL17732299 | 0.85 | TTR (0.85) | APPMAPTBACE1TTRMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7163961-B1 | Drugs, foods and oral compositions containing stilbene-type compounds | SUNSTAR INC. (JP) | 2007-01-16 | — | — | US | disclosed |
| EP-1161944-A1 | DRUGS, FOODS AND ORAL COMPOSITIONS CONTAINING STILBENE-TYPE COMPOUNDS | Sunstar Inc. (JP) | 2001-12-12 | — | — | EP | disclosed |