Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 20/20 | 0.52 |
| ▸ | S1PR5 | Q9H228 | 3/20 | 0.46 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL411140 | 0.91 | S1PR1 (0.49) | S1PR1S1PR5S1PR3 | |
| SCHEMBL410811 | 0.90 | S1PR1 (0.62) | S1PR1S1PR5S1PR3 | |
| SCHEMBL409645 | 0.88 | S1PR1 (0.58) | S1PR1S1PR5S1PR3 | |
| SCHEMBL406840 | 0.85 | S1PR1 (0.54) | S1PR1S1PR5S1PR3 | |
| SCHEMBL558527 | 0.83 | S1PR1 (0.53) | S1PR1S1PR5S1PR3 | |
| SCHEMBL406955 | 0.83 | S1PR1 (0.54) | S1PR1S1PR3 | |
| SCHEMBL409492 | 0.82 | S1PR1 (0.58) | S1PR1S1PR5S1PR3 | |
| SCHEMBL408484 | 0.82 | S1PR1 (0.50) | S1PR1S1PR5S1PR3 | |
| SCHEMBL410337 | 0.82 | S1PR1 (0.51) | S1PR1S1PR3 | |
| SCHEMBL409831 | 0.81 | S1PR1 (0.52) | S1PR1S1PR5S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-A1 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010112461-A1 | OXADIAZOLE DERIVATIVES | MERCK SERONO S.A. (CH) | 2010-10-07 | — | — | WO | disclosed |