Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 7/20 | 0.49 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.48 |
| ▸ | GFER | P55789 | 1/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.44 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.43 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.43 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | RARA | P10276 | 1/20 | 0.42 |
| ▸ | RARB | P10826 | 1/20 | 0.42 |
| ▸ | RARG | P13631 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL409116 | 1.00 | S1PR1 (0.49) | S1PR1GPBAR1GFERTTRTAS1R3 | |
| SCHEMBL405390 | 1.00 | S1PR1 (0.49) | S1PR1GPBAR1GFERTTRTAS1R3 | |
| SCHEMBL410127 | 1.00 | S1PR1 (0.49) | S1PR1GPBAR1GFERTTRTAS1R3 | |
| Hydrochloric Acid SCHEMBL2810962 | 0.99 | S1PR1 (0.48) | S1PR1GPBAR1GFERTTRTAS1R3 | |
| SCHEMBL2484886 | 0.92 | S1PR1 (0.52) | S1PR1GPBAR1GFERTTRRARA | |
| SCHEMBL18373542 | 0.91 | GFER (0.47) | S1PR1GPBAR1GFERTTRGAA | |
| SCHEMBL1725667 | 0.88 | S1PR1 (0.48) | S1PR1GPBAR1GFERTTRRARA | |
| SCHEMBL410194 | 0.87 | S1PR1 (0.50) | S1PR1GPBAR1GFERGAAHPGD | |
| Hydrochloric Acid SCHEMBL16817128 | 0.86 | S1PR1 (0.49) | S1PR1GPBAR1GFERGAAHPGD | |
| SCHEMBL20702699 | 0.82 | S1PR1 (0.48) | S1PR1GPBAR1GFERGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414342-A1 | OXADIAZOLE DERIVATIVES | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |