Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 20/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL505259 | 0.85 | DHODH (0.58) | DHODH | |
| SCHEMBL10213024 | 0.78 | DHODH (0.80) | DHODH | |
| SCHEMBL505596 | 0.73 | DHODH (0.63) | DHODH | |
| SCHEMBL10211970 | 0.71 | DHODH (1.00) | DHODH | |
| SCHEMBL505170 | 0.71 | DHODH (0.63) | DHODH | |
| SCHEMBL505260 | 0.70 | DHODH (0.56) | DHODH | |
| SCHEMBL505407 | 0.69 | DHODH (0.82) | DHODH | |
| SCHEMBL505258 | 0.69 | DHODH (0.55) | DHODH | |
| SCHEMBL29100989 | 0.69 | MRGPRX4 (0.50) | — | |
| SCHEMBL30630386 | 0.69 | MRGPRX4 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2414328-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | Merck Serono S.A. (CH) | 2012-02-08 | — | — | EP | disclosed |
| WO-2010115736-A2 | DIHYDROOROTATE DEHYDROGENASE INHIBITORS | MERCK SERONO S.A. (CH) | 2010-10-14 | — | — | WO | disclosed |