Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | APP | P05067 | 1/20 | 0.48 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | LIG1 | P18858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Phthalic Acid SCHEMBL5363488 | 1.00 | CYP3A4 (0.61) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL11496920 | 0.86 | CYP3A4 (0.83) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL10839688 | 0.86 | CYP3A4 (0.83) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| Phthalic Acid SCHEMBL710707 | 0.84 | CYP3A4 (0.86) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| Phthalic Acid SCHEMBL710708 | 0.84 | CYP3A4 (0.86) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| Phthalic Acid SCHEMBL23929049 | 0.84 | CYP3A4 (0.86) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| SCHEMBL87635 | 0.84 | CYP3A4 (0.86) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| Benzene SCHEMBL7689916 | 0.84 | CYP3A4 (0.86) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| Bicarbonate SCHEMBL20838539 | 0.83 | CYP3A4 (0.83) | CYP3A4ALDH1A1HSD17B10TSHRMAPT | |
| Toluene SCHEMBL11320582 | 0.83 | CYP3A4 (0.51) | CYP3A4ALDH1A1HSD17B10TSHRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7309729-B1 | Aqueous additive systems for polymeric matrices | ROHM AND HAAS COMPANY (US) | 2007-12-18 | — | — | US | disclosed |
| US-7238742-B2 | Aqueous additive systems for polymeric matrices | ROHM AND HAAS COMPANY (US) | 2007-07-03 | — | — | US | disclosed |
| EP-1033390-B1 | Aqueous additive systems for polymeric matrices | ROHM & HAAS (US) | 2006-05-03 | — | — | EP | disclosed |
| US-20030199628-A1 | Aqueous additive systems for polymeric matrices | ROHM AND HAAS COMPANY | 2003-10-23 | — | — | US | disclosed |
| EP-1033390-A1 | Aqueous additive systems for polymeric matrices | ROHM AND HAAS COMPANY (US) | 2000-09-06 | — | — | EP | disclosed |