Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX1 | P07099 | 11/20 | 0.60 |
| ▸ | CASP2 | P42575 | 1/20 | 0.54 |
| ▸ | NAAA | Q02083 | 2/20 | 0.50 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.50 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5363824 | 1.00 | EPHX1 (0.60) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL16500265 | 0.89 | EPHX1 (0.54) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL7876750 | 0.81 | EPHX1 (0.60) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL176011 | 0.80 | — | — | |
| SCHEMBL10488375 | 0.79 | EPHX1 (0.64) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL12266952 | 0.79 | EPHX1 (0.64) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL10916993 | 0.79 | EPHX1 (0.64) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL8293274 | 0.79 | EPHX1 (0.64) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL11419656 | 0.79 | EPHX1 (0.64) | EPHX1CASP2NAAAZDHHC20ZDHHC2 | |
| SCHEMBL8293272 | 0.79 | EPHX1 (0.64) | EPHX1CASP2NAAAZDHHC20ZDHHC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007153758-A | METHOD FOR PRODUCING 3-ARYLAMINO-2-ALKOXYCARBONYL-4-QUINOLONE COMPOUND | DAINIPPON INK & CHEM INC | 2007-06-21 | — | — | JP | disclosed |