Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.74 |
| ▸ | DDB1 | Q16531 | 16/20 | 0.74 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.40 |
| ▸ | EHMT1 | Q9H9B1 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22612114 | 0.85 | CRBN (1.00) | CRBNDDB1 | |
| SCHEMBL18283225 | 0.76 | CRBN (0.51) | CRBNDDB1SMN1; SMN2EHMT2EHMT1 | |
| SCHEMBL5798857 | 0.75 | DDB1 (0.70) | CRBNDDB1SMN1; SMN2 | |
| SCHEMBL18283223 | 0.74 | CRBN (0.49) | CRBNDDB1SMN1; SMN2EHMT2EHMT1 | |
| SCHEMBL2790063 | 0.72 | SMN1; SMN2 (1.00) | CRBNDDB1SMN1; SMN2 | |
| SCHEMBL4009867 | 0.70 | CRBN (0.51) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL10640790 | 0.70 | KMT2A (0.59) | CRBNDDB1SMN1; SMN2 | |
| SCHEMBL27767730 | 0.69 | CRBN (0.71) | CRBNDDB1SMN1; SMN2 | |
| SCHEMBL8306896 | 0.69 | CRBN (0.50) | CRBNDDB1EHMT2EHMT1APOBEC3G | |
| SCHEMBL10644845 | 0.68 | DDB1 (0.76) | CRBNDDB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7166694-B2 | Vaccine against cancerous diseases which is based on mimotopes of antigens expressed on tumor cells | BIOLIFE SCIENCE QLD LIMITED (AU) | 2007-01-23 | — | — | US | disclosed |
| US-20050100551-A1 | Vaccine against cancerous diseases which is based on mimotopes of antigens expressed on tumor cells | BIOLIFE SCIENCE QLD LIMITED (AU) | 2005-05-12 | — | — | US | disclosed |
| US-4853467-A | Nitrogen containing derivatives of epipodophyllotoxin glucosides | BRISTOL-MYERS COMPANY (US) | 1989-08-01 | — | — | US | disclosed |
| EP-0291957-A2 | Nitrogen containing derivatives of epipodophyllotoxin glucosides, a process for preparing them and pharmaceutical compositions | Bristol-Myers Squibb Company (US) | 1988-11-23 | — | — | EP | disclosed |