Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.87 |
| ▸ | ADORA1 | P30542 | 19/20 | 0.87 |
| ▸ | GNRHR | P30968 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4521040 | 0.93 | ADORA2A (1.00) | ADORA2AADORA1GNRHR | |
| SCHEMBL4512082 | 0.86 | ADORA2A (1.00) | ADORA2AADORA1GNRHR | |
| SCHEMBL4525961 | 0.83 | ADORA2A (0.81) | ADORA2AADORA1 | |
| SCHEMBL4522104 | 0.83 | ADORA2A (0.86) | ADORA2AADORA1 | |
| SCHEMBL4515954 | 0.82 | ADORA2A (0.87) | ADORA2AADORA1 | |
| SCHEMBL4526094 | 0.81 | ADORA2A (0.86) | ADORA2AADORA1 | |
| SCHEMBL4515637 | 0.80 | ADORA2A (0.79) | ADORA2AADORA1 | |
| SCHEMBL4528775 | 0.80 | ADORA2A (1.00) | ADORA2AADORA1 | |
| SCHEMBL4531666 | 0.80 | ADORA2A (0.77) | ADORA2AADORA1 | |
| SCHEMBL4530396 | 0.80 | ADORA2A (0.87) | ADORA2AADORA1GNRHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007035873-A1 | PURINONE DERIVATIVES FOR TREATING NEURODEGENERATIVE DISEASES | PHARMACOPEIA, INC. (US) | 2007-03-29 | — | — | WO | disclosed |