SCHEMBL5364744

SCHEMBL5364744

CCCCCCCCCCCCCCCC(=O)OC[C@H]1O[C@@H](n2cnc3c(N)ncnc32)C(O)C1O

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EHMT1 Q9H9B1 1/20 0.69
PRKACA P17612 2/20 0.69
RXFP1 Q9HBX9 1/20 0.66
AHCY P23526 1/20 0.63
MARS1 P56192 1/20 0.62
DNPH1 O43598 1/20 0.62
PRKAB2 O43741 1/20 0.62
TRPM2 O94759 1/20 0.62
LDHA P00338 1/20 0.62
ADRB2 P07550 1/20 0.62
FBP1 P09467 1/20 0.62
SRC P12931 1/20 0.62
ADORA1 P30542 1/20 0.62
P2RY2 P41231 1/20 0.62
P2RY1 P47900 1/20 0.62
PRKAG1 P54619 1/20 0.62
PRKAA2 P54646 1/20 0.62
PDE4D Q08499 1/20 0.62
KCNH2 Q12809 1/20 0.62
PRKAA1 Q13131 1/20 0.62

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5561909 1.00 EHMT1 (0.69) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL14696397 1.00 EHMT1 (0.69) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL12800893 1.00 EHMT1 (0.69) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL1669299 1.00 EHMT1 (0.69) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL5375737 1.00 EHMT1 (0.69) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL10587414 1.00 EHMT1 (0.69) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL10587627 0.99 EHMT1 (0.71) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL10585105 0.96 EHMT1 (0.69) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL7236374 0.95 EHMT1 (0.63) EHMT1PRKACARXFP1AHCYMARS1
SCHEMBL6536155 0.93 PRKACA (0.67) EHMT1PRKACAAHCYMARS1DNPH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169765-B1 Acyl deoxyribonucleoside derivatives and uses thereof WELLSTAT THERAPEUTICS CORPORATION (US) 2007-01-30 US disclosed
EP-0712629-B1 Acyl deoxyribonucleoside derivatives and uses thereof WELLSTAT THERAPEUTICS CORP (US) 2003-06-18 EP disclosed
US-6348451-B1 WOUND HEALING AGENTS FOR ANIMALS PRO-NEURON, INC. 2002-02-19 US disclosed
US-6306834-B1 METHODS OF TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED BIOLOGICAL DAMAGE, METHODS FOR IMPROVING WOUND HEALING AND TISSUE REPAIR, COMPRISING ADMINISTERING THE COMPOSITIONS OF THE PRESENT INVENTION TO AN ANIMAL. PRO-NEURON, INC. 2001-10-23 US disclosed
US-6297222-B1 TREATING OR PREVENTING RADIATION, MUTAGEN AND SUNLIGHT-INDUCED BIOLOGICAL DAMAGE, AND METHODS FOR IMPROVING WOUND HEALING AND TISSUE REPAIR PRO-NEURON, INC. 2001-10-02 US disclosed
US-6103701-A ADMINISTERING COMPOSITIONS COMPRISING ACYL DERIVATIVES OF 2'-DEOXYRIBONUCLEOSIDES; FOR IMPROVING WOUND HEALING AND TISSUE REPAIR VON BORSTEL REID WARREN (US) 2000-08-15 US disclosed
US-6020322-A Acyl deoxyribonucleoside derivatives and uses thereof PRO-NEURON, INC. (US) 2000-02-01 US disclosed
EP-0355131-B1 ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF PRO NEURON INC (US) 1996-09-04 EP disclosed
EP-0712629-A1 Acyl deoxyribonucleoside derivatives and uses thereof PRO-NEURON, INC. (US) 1996-05-22 EP disclosed
EP-0355131-A1 ACYL DEOXYRIBONUCLEOSIDE DERIVATIVES AND USES THEREOF PRO-NEURON, INC. (US) 1990-02-28 EP disclosed