Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.60 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.60 |
| ▸ | FAP | Q12884 | 4/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5361014 | 0.97 | DPP4 (0.58) | DPP4CHRM1FAP | |
| SCHEMBL8278521 | 0.86 | DPP4 (0.64) | DPP4CHRM1 | |
| SCHEMBL5354009 | 0.85 | DPP4 (0.63) | DPP4CHRM1FAP | |
| SCHEMBL5370066 | 0.82 | DPP4 (0.62) | DPP4CHRM1FAP | |
| SCHEMBL5364466 | 0.82 | DPP4 (0.66) | DPP4CHRM1FAP | |
| SCHEMBL5358438 | 0.82 | DPP4 (0.39) | DPP4CHRM1FAP | |
| SCHEMBL5366092 | 0.82 | DPP4 (0.61) | DPP4CHRM1FAP | |
| SCHEMBL6381749 | 0.80 | DPP4 (0.75) | DPP4CHRM1FAP | |
| SCHEMBL5358919 | 0.80 | DPP4 (0.64) | DPP4CHRM1FAP | |
| SCHEMBL13200756 | 0.80 | DPP4 (0.64) | DPP4CHRM1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217711-B2 | Piperazin-1-yl and 2-([1,4]diazepan-1-yl)-imidazo[4,5-d]-pyridazin-4-ones, the preparation thereof and their use as pharmaceutical compositions | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2007-05-15 | — | — | US | disclosed |