Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | CDC25A | P30304 | 1/20 | 0.42 |
| ▸ | CDC25B | P30305 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.40 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | MYC | P01106 | 1/20 | 0.38 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL705602 | 0.95 | KDM4E (0.42) | KDM4EHSD17B10TDP1L3MBTL1SERPINE1 | |
| SCHEMBL2352254 | 0.93 | KDM4E (0.49) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL5374162 | 0.91 | SERPINE1 (0.41) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL31153150 | 0.90 | TDP1 (0.52) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL14839238 | 0.88 | TSHR (0.51) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL31153128 | 0.88 | TSHR (0.51) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL5437825 | 0.88 | CDC25A (0.47) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL31153140 | 0.88 | TSHR (0.51) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL31153125 | 0.88 | TSHR (0.51) | KDM4EHSD17B10CDC25ACDC25BTDP1 | |
| SCHEMBL31153159 | 0.88 | TSHR (0.51) | KDM4EHSD17B10CDC25ACDC25BTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7241855-B2 | Method for the manufacture of polyesters | ZIMMER AKTIENGESELLSCHAFT (DE) | 2007-07-10 | — | — | US | claimed |
| CN-1829758-A | Aliphatic-aromatic polyetherester compositions, articles, films, coating and laminates and processes for producing same | DU PONT (US) | 2006-09-06 | — | — | CN | disclosed |
| CN-1102967-C | Polyester yarn | DU PONT (US) | 2003-03-12 | — | — | CN | disclosed |
| CN-1254388-A | Polyester yarn | DU PONT (US) | 2000-05-24 | — | — | CN | disclosed |