Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 3/20 | 0.63 |
| ▸ | LSS | P48449 | 2/20 | 0.52 |
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA9 | Q16790 | 1/20 | 0.43 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | EEF2K | O00418 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17623715 | 0.83 | CYP19A1 (0.59) | CYP19A1LSSIDO1TRPV4MEN1 | |
| SCHEMBL3119830 | 0.83 | CYP19A1 (0.63) | CYP19A1LSSIDO1TRPV4CA12 | |
| SCHEMBL2064469 | 0.83 | CYP19A1 (0.63) | CYP19A1LSSIDO1MEN1ALDH1A1 | |
| SCHEMBL3120110 | 0.80 | CYP19A1 (0.59) | CYP19A1LSSIDO1TRPV4MEN1 | |
| SCHEMBL22558321 | 0.80 | CYP19A1 (0.59) | CYP19A1LSSMEN1ALDH1A1PKM | |
| SCHEMBL12203599 | 0.79 | CYP19A1 (0.58) | CYP19A1LSSIDO1ALDH1A1KMT2A | |
| SCHEMBL26212971 | 0.79 | LSS (0.59) | CYP19A1LSSALDH1A1CA12CA1 | |
| SCHEMBL6071317 | 0.79 | TSHR (0.65) | CYP19A1LSSIDO1ALDH1A1CA12 | |
| SCHEMBL1714909 | 0.79 | CYP19A1 (0.58) | CYP19A1LSSIDO1TRPV4MEN1 | |
| SCHEMBL4613568 | 0.79 | CYP19A1 (0.67) | CYP19A1LSSIDO1ALDH1A1KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007108743-A2 | NOVEL QUINAZOLINES AS 5-HT6 MODULATORS II | ASTRAZENECA AB (SE) | 2007-09-27 | — | — | WO | disclosed |