SCHEMBL5366417

SCHEMBL5366417

CC(C)CC(C)OC(=O)C1CCCC(C(=O)OC(C)CC(C)C)C1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PSMB5 P28074 2/20 0.34
HPGD P15428 1/20 0.33
CHRM2 P08172 1/20 0.33
CHRM4 P08173 1/20 0.33
CHRM1 P11229 1/20 0.33
CHRM3 P20309 1/20 0.33
EPHX2 P34913 1/20 0.33
CTSL P07711 2/20 0.33
CTSB P07858 2/20 0.33
CTSH P09668 2/20 0.33
CTSK P43235 2/20 0.33
RAB9A P51151 1/20 0.33
CYP19A1 P11511 1/20 0.33
KMT2A Q03164 3/20 0.32
SMN1; SMN2 Q16637 2/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
MEN1 O00255 1/20 0.32
POLB P06746 1/20 0.32
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13954784 0.90 CHRM2 (0.33) PSMB5HPGDCHRM2CHRM4CHRM1
SCHEMBL5369156 0.87 EPHX2 (0.38) PSMB5HPGDCHRM2CHRM4CHRM1
SCHEMBL5372188 0.85 HPGD (0.39) HPGDCHRM2CHRM4CHRM1CHRM3
SCHEMBL5364583 0.82 EPHX2 (0.39) HPGDCHRM2CHRM4CHRM1CHRM3
SCHEMBL1246359 0.80 TSHR (0.37) HPGDCHRM2CHRM4CHRM1CHRM3
SCHEMBL28483461 0.80 ANPEP (0.38) HPGDEPHX2LMNA
SCHEMBL7184412 0.79 CHRM2 (0.36) HPGDCHRM2CHRM4CHRM1CHRM3
SCHEMBL13935308 0.78 PPM1B (0.33) PSMB5
SCHEMBL5363137 0.77 CHRM2 (0.35) HPGDCHRM2CHRM4CHRM1CHRM3
SCHEMBL2984985 0.77 HPGD (0.41) HPGDCHRM2CHRM4CHRM1CHRM3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US claimed
EP-1194396-B1 SELECTED CYCLOHEXANE-1,3- AND 1,4-DICARBOXYLIC ACID ESTERS BASF AG (DE) 2005-11-09 EP claimed
US-7208545-B1 Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters BASF AKTIENGESELLSCHAFT (DE) 2007-04-24 US disclosed