Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | KCNJ6 | P48051 | 1/20 | 0.31 |
| ▸ | KCNJ5 | P48544 | 1/20 | 0.31 |
| ▸ | KCNJ3 | P48549 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367028 | 1.00 | AOC3 (0.34) | AOC3GAAHPGDALOX15ADORA3 | |
| SCHEMBL5357039 | 0.91 | AOC3 (0.37) | AOC3GAAHPGDALOX15ADORA3 | |
| SCHEMBL5354109 | 0.90 | RXFP1 (0.39) | AOC3MEN1KMT2ATP53MAPT | |
| SCHEMBL5354113 | 0.90 | RXFP1 (0.39) | AOC3MEN1KMT2ATP53MAPT | |
| SCHEMBL5366844 | 0.87 | AOC3 (0.33) | AOC3 | |
| SCHEMBL5348143 | 0.87 | AOC3 (0.33) | AOC3 | |
| SCHEMBL5348137 | 0.87 | AOC3 (0.33) | AOC3 | |
| SCHEMBL5367031 | 0.82 | AOC3 (0.33) | AOC3GAAHPGDALOX15ADORA3 | |
| SCHEMBL5352834 | 0.81 | RXFP1 (0.41) | AOC3HPGDMEN1KMT2ATP53 | |
| SCHEMBL5350418 | 0.78 | AOC3 (0.35) | AOC3TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7217723-B2 | Substituted benzothiophenes, e.g., 7Z)-7-hydroxyimino-4,5,6,7-tetrahydro-benzo[b]thiophene-3-sulfonic acid [2-(4-fluorophenyl)-2-hydroxyethyl]-methyl-amide; treating allergies such as atopic dermatitis, allergic coryza, bronchial asthma, hypersensitive pneumoniac and pulmonary aspergillosis. | EISAI CO., LTD. (JP) | 2007-05-15 | — | — | US | disclosed |