Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | GPBAR1 | Q8TDU6 | 3/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 2/20 | 0.39 |
| ▸ | CYSLTR1 | Q9Y271 | 2/20 | 0.39 |
| ▸ | NR5A1 | Q13285 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | NPY1R | P25929 | 1/20 | 0.34 |
| ▸ | NPY2R | P49146 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5134856 | 0.89 | PDE2A (0.36) | LTA4HNR5A1MAPT | |
| SCHEMBL5445426 | 0.86 | NR5A1 (0.50) | LTA4HGPBAR1CYSLTR2CYSLTR1NR5A1 | |
| SCHEMBL45837 | 0.86 | NR5A1 (0.50) | LTA4HGPBAR1CYSLTR2CYSLTR1NR5A1 | |
| SCHEMBL9744615 | 0.86 | NR5A1 (0.50) | LTA4HGPBAR1CYSLTR2CYSLTR1NR5A1 | |
| SCHEMBL13370102 | 0.86 | NR5A1 (0.50) | LTA4HGPBAR1CYSLTR2CYSLTR1NR5A1 | |
| SCHEMBL8144724 | 0.86 | NPC1 (0.45) | LMNANPC1RAB9AALDH1A1KDM4E | |
| SCHEMBL7141357 | 0.84 | GPBAR1 (0.46) | LTA4HGPBAR1CYSLTR2CYSLTR1NR5A1 | |
| SCHEMBL29463600 | 0.84 | GPBAR1 (0.46) | LTA4HGPBAR1CYSLTR2CYSLTR1NR5A1 | |
| SCHEMBL6474039 | 0.80 | NPC1 (0.45) | GPBAR1CYSLTR2CYSLTR1LMNANPC1 | |
| SCHEMBL10942650 | 0.80 | GPBAR1 (0.43) | LTA4HGPBAR1CYSLTR2CYSLTR1NR5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2007063250-A | SYNTHESIS AND USE, AS ULTRAVIOLET ABSORBER, OF 2-ALKOXY-4,6-BIS[4-(2H-BENZOTRIAZOL-2-YL)-3-HYDROXYPHENOXY]-1,3,5-TRIAZINE, 2-ARYLOXY-4,6-BIS[4-(2H-BENZOTRIASOL-2-YL)-3-HYDROXYPHENOXY]-1,3,5-TRIAZINE, 2-ALKOXY-4,6-BIS[4-(DIMETHYLAMINO)ANILINO]-1,3,5-TRIAZINE, AND 2-ARYLOXY-4,6-BIS[4-(DIMETHYLAMINO)ANILINO]-1,3,5-TRIAZINE | SHIPRO KASEI KAISHA LTD | 2007-03-15 | — | — | JP | disclosed |