Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCGR | P47871 | 20/20 | 0.73 |
| ▸ | GLP1R | P43220 | 4/20 | 0.59 |
| ▸ | GIPR | P48546 | 4/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367519 | 1.00 | GCGR (0.73) | GCGRGLP1RGIPR | |
| SCHEMBL5362783 | 0.92 | GCGR (0.72) | GCGRGLP1RGIPR | |
| SCHEMBL5362786 | 0.92 | GCGR (0.72) | GCGRGLP1RGIPR | |
| SCHEMBL5360877 | 0.91 | GCGR (0.62) | GCGRGLP1RGIPR | |
| SCHEMBL5360880 | 0.91 | GCGR (0.62) | GCGRGLP1RGIPR | |
| SCHEMBL14387853 | 0.90 | GCGR (0.68) | GCGRGLP1RGIPR | |
| SCHEMBL5366553 | 0.89 | GCGR (0.60) | GCGRGLP1RGIPR | |
| SCHEMBL5364539 | 0.88 | GCGR (0.59) | GCGRGLP1RGIPR | |
| SCHEMBL5364543 | 0.88 | GCGR (0.59) | GCGRGLP1RGIPR | |
| SCHEMBL5364393 | 0.85 | GCGR (0.78) | GCGRGLP1RGIPR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7301036-B2 | Cyclic guanidines, compositions containing such compounds and methods of use | MERCK & CO., INC. (US) | 2007-11-27 | — | — | US | disclosed |