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SCHEMBL5367696

SCHEMBL5367696

Cc1ccc2c(c1)N(c1ccc(NC(C3CCCC3)N(C=O)OC(C)(C)C)cn1)C(=O)N(C(C)C)N=C2C1CCCCC1

nearest known ligand 0.52

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ PTH1R Q03431 19/20 0.52
▸ CCKBR P32239 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5347210 0.77 PTH1R (0.65) PTH1R
SCHEMBL5352610 0.77 PTH1R (0.54) PTH1R
SCHEMBL5348779 0.76 PTH1R (0.85) PTH1R
SCHEMBL5345422 0.76 PTH1R (0.51) PTH1RCCKBR
SCHEMBL5370196 0.75 PTH1R (0.72) PTH1R
SCHEMBL5367690 0.75 PTH1R (0.52) PTH1RCCKBR
SCHEMBL5320984 0.72 PTH1R (0.63) PTH1R
SCHEMBL5343663 0.70 PTH1R (0.62) PTH1R
SCHEMBL5362907 0.70 PTH1R (0.55) PTH1R
SCHEMBL5370417 0.69 PTH1R (0.55) PTH1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007135350-A1 BENZOTRIAZEPINONE DERIVATIVES JAMES BLACK FOUNDATION (GB) 2007-11-29 — — WO disclosed