Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.59 |
| ▸ | GAA | P10253 | 3/20 | 0.59 |
| ▸ | MAPT | P10636 | 8/20 | 0.54 |
| ▸ | HTT | P42858 | 4/20 | 0.54 |
| ▸ | LMNA | P02545 | 4/20 | 0.54 |
| ▸ | BLM | P54132 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.49 |
| ▸ | GFER | P55789 | 2/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL422634 | 0.79 | KDM4E (0.63) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL10802825 | 0.79 | KDM4E (0.48) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL3236045 | 0.78 | KDM4E (1.00) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL2871452 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL18721830 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL9453945 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL2871450 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL3243436 | 0.78 | KDM4E (0.61) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL30632281 | 0.78 | KDM4E (0.56) | KDM4EALDH1A1GAAMAPTHTT | |
| SCHEMBL29101968 | 0.77 | KDM4E (0.46) | KDM4EALDH1A1GAAMAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7304164-B1 | Melt-cast explosive material | THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE ARMY (US) | 2007-12-04 | — | — | US | disclosed |
| EP-0293742-B1 | PROCESS FOR THE PRODUCTION OF 4-NITRO-5-IMIDAZOLYLETHERS AND -THIOETHERS | BASF Aktiengesellschaft (DE) | 1992-07-22 | — | — | EP | disclosed |
| US-4900825-A | REACTING DINITROIMIDAZOLES WITH ALCOHOLS OR MERCAPTANS | BASF AKTIENGSELLSCHAFT (DE) | 1990-02-13 | — | — | US | disclosed |
| EP-0348803-A1 | Process for the preparation of 5-cyano-4-nitroimidazoles | BASF Aktiengesellschaft (DE) | 1990-01-03 | — | — | EP | disclosed |
| EP-0337255-A1 | Process for the preparation of 4-nitro-5-aminoimidazoles | BASF Aktiengesellschaft (DE) | 1989-10-18 | — | — | EP | disclosed |
| EP-0293742-A1 | Process for the production of 4-nitro-5-imidazolylethers and -thioethers | BASF Aktiengesellschaft (DE) | 1988-12-07 | — | — | EP | disclosed |