Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 18/20 | 0.62 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.49 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5367887 | 1.00 | DPP4 (0.62) | DPP4OPRM1OPRD1FAP | |
| SCHEMBL5371937 | 0.84 | DPP4 (0.60) | DPP4OPRM1OPRD1FAP | |
| SCHEMBL5371942 | 0.84 | DPP4 (0.60) | DPP4OPRM1OPRD1FAP | |
| SCHEMBL5376590 | 0.77 | DPP4 (1.00) | DPP4OPRM1OPRD1 | |
| SCHEMBL5376592 | 0.77 | DPP4 (1.00) | DPP4OPRM1OPRD1 | |
| SCHEMBL5376155 | 0.77 | DPP4 (1.00) | DPP4OPRM1OPRD1 | |
| SCHEMBL5376148 | 0.77 | DPP4 (1.00) | DPP4OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL6184642 | 0.76 | DPP4 (0.97) | DPP4OPRM1OPRD1 | |
| SCHEMBL26876626 | 0.73 | DPP4 (0.60) | DPP4FAP | |
| SCHEMBL719100 | 0.72 | DPP4 (0.46) | DPP4OPRM1OPRD1FAP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7205409-B2 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2007-04-17 | — | — | US | disclosed |
| US-20050131019-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | ABBVIE INC. | 2005-06-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131019-A1 | Pharmaceutical compositions as inhibitors of dipeptidyl peptidase-IV (DPP-IV) | DPP4, DPP3, DPP7 | DPP4 1/4885OPRM1 2511/4885OPRD1 1917/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.