Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | NPC1 | O15118 | 4/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | CES2 | O00748 | 3/20 | 0.39 |
| ▸ | CES1 | P23141 | 3/20 | 0.39 |
| ▸ | PHGDH | O43175 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | HTT | P42858 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPY1R | P25929 | 1/20 | 0.33 |
| ▸ | NPY2R | P49146 | 1/20 | 0.33 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14559443 | 1.00 | MAPT (0.48) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL5368776 | 1.00 | MAPT (0.48) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL14559440 | 0.96 | MAPT (0.45) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL5375917 | 0.87 | MAPT (0.48) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL14559432 | 0.87 | KMT2A (0.48) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL5375914 | 0.87 | MAPT (0.48) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL14559441 | 0.87 | MAPT (0.48) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL14559434 | 0.86 | KMT2A (0.48) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL14559442 | 0.84 | PHGDH (0.36) | MAPTKMT2AMEN1TSHRMAPK1 | |
| SCHEMBL14559453 | 0.84 | MAPT (0.41) | MAPTKMT2AMEN1TSHRMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186829-B1 | Aryl-substituted heterocyclic enaminones | BAYER AKTIENGESELLSCHAFT (DE) | 2007-03-06 | — | — | US | disclosed |
| US-20060069253-A1 | Aryl-substituted heterocyclic enaminones | FISCHER REINER | 2006-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060069253-A1 | Aryl-substituted heterocyclic enaminones | DDT, NPY4R, NPY5R | MAPT 4366/4885KMT2A 664/4885MEN1 2635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.