SCHEMBL5369

SCHEMBL5369

C[Si](C)(C)N[Si](C)(C)C.[NaH]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22981962 1.00
SCHEMBL1949806 0.95
SCHEMBL4790946 0.95
SCHEMBL29212527 0.95
SCHEMBL4964921 0.94
SCHEMBL7649 0.94
SCHEMBL1207974 0.89
SCHEMBL9613 0.89
Ammonia Solution, Strong SCHEMBL8613097 0.89
SCHEMBL5084309 0.89

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3919 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122010807-A Preparation method of negative charge highly delocalized sulfimide alkali metal salt 华中科技大学 2026-05-12 CN claimed
CN-113620949-B Synthesis method of antitumor compound and intermediate thereof 药捷安康(南京)科技股份有限公司 2025-05-09 CN claimed
CN-119504724-A Intermediates and methods of bicyclic compounds as CDK inhibitors 百济神州(北京)生物科技有限公司 2025-02-25 CN claimed
CN-119456218-A Efficient floatation process for minerals 郑州大学 2025-02-18 CN claimed
CN-119060068-A Intermediates and methods for compounds that degrade EGFR kinase 百济神州(北京)生物科技有限公司 2024-12-03 CN claimed
US-20240368063-A1 PREPARATION METHOD, INTERMEDIATE COMPOUNDS, AND SYNTHESIS METHOD FOR A CLASS OF ANTHRACENE-DERIVED TOXINS IN ORGANIC CHEMISTRY WUYAN PHARMACEUTICAL TECHNOLOGY (SHANGHAI) CO., LTD (CN) 2024-11-07 US claimed
CN-116969823-B Preparation method of squaric acid intermediate 山东华安新材料有限公司 2024-10-29 CN claimed
CN-118530141-A Aromatic hydrazide compound, preparation method and sterilization application thereof 聊城大学 2024-08-23 CN claimed
US-20240217984-A1 PREPARATION METHOD OF TRILACICLIB AND PRECURSORS OF TRILACICLIB CHUNGHWA CHEMICAL SYNTHESIS & BIOTECH CO. LTD. (TW) 2024-07-04 US claimed
CN-118221559-A Nemactetvir intermediate impurity and preparation method of hydrochloride thereof 上海科胜药物研发有限公司 2024-06-21 CN claimed
WO-1997042205-A1 3-DESCLADINOSE-2,3-ANHYDROERYTHROMYCIN DERIVATIVES ABBOTT LABORATORIES (US) 1997-11-13 WO claimed
US-5426233-A Contacting dihalophenone type compound with chiral hydroxylating compound at low temperature SCHERING CORPORATION (US) 1995-06-20 US claimed
EP-0281177-B1 A SYNTHESIS FOR BETA-LACTAMS WITH THE AID OF A METAL COMPOUND RIJKSUNIVERSITEIT UTRECHT (NL) 1993-09-01 EP claimed
WO-1992017433-A1 PREPARATION OF CHIRAL HYDROXYKETONES SCHERING CORPORATION (US) 1992-10-15 WO claimed
EP-0506341-A1 Preparation of chiral hydroxyketones SCHERING CORPORATION (US) 1992-09-30 EP claimed
EP-0442576-A1 Synthesis of cis-beta-lactams with the aid of an alkali metal compound RIJKSUNIVERSITEIT UTRECHT (NL) 1991-08-21 EP claimed
CN-1048215-A Adopt improving one's methods of the synthetic beta-lactam of metallic compound UNIV UTRECHT (NL) 1991-01-02 CN claimed
EP-0404267-A1 Improved synthesis of beta-lactams using a metal compound RIJKSUNIVERSITEIT UTRECHT (NL) 1990-12-27 EP claimed
EP-0281177-A1 A synthesis for beta-lactams with the aid of a metal compound RIJKSUNIVERSITEIT UTRECHT (NL) 1988-09-07 EP claimed
CN-88100703-A Synthesis of beta-lactams with metal compounds 1988-08-17 CN claimed