Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377725 | 0.78 | BACE1 (0.41) | BACE1CTSD | |
| SCHEMBL6895439 | 0.78 | BACE1 (0.41) | BACE1CTSD | |
| SCHEMBL5381675 | 0.75 | BACE1 (0.45) | BACE1CTSD | |
| SCHEMBL1521907 | 0.75 | BACE1 (0.38) | BACE1CTSD | |
| SCHEMBL3357117 | 0.75 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL3357121 | 0.75 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL5375742 | 0.75 | BACE1 (0.48) | BACE1CTSD | |
| SCHEMBL5579079 | 0.72 | BACE1 (0.62) | BACE1CTSD | |
| SCHEMBL5579001 | 0.71 | BACE1 (0.63) | BACE1CTSD | |
| SCHEMBL5474023 | 0.71 | BACE1 (0.47) | BACE1CTSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |