Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL103825 | 0.78 | GRM5 (0.44) | MAPTL3MBTL1 | |
| Hydrochloric Acid SCHEMBL103140 | 0.77 | GRM5 (0.43) | MAPTL3MBTL1 | |
| SCHEMBL102444 | 0.74 | GRM5 (0.38) | — | |
| SCHEMBL103237 | 0.74 | GRM5 (0.38) | MAPTL3MBTL1 | |
| SCHEMBL103189 | 0.74 | GRM5 (0.57) | — | |
| SCHEMBL1203333 | 0.73 | TLR8 (0.36) | — | |
| SCHEMBL101175 | 0.72 | GRM5 (0.39) | — | |
| Hydrochloric Acid SCHEMBL103085 | 0.71 | GRM5 (0.38) | — | |
| SCHEMBL102878 | 0.71 | GRM5 (0.35) | — | |
| SCHEMBL102132 | 0.71 | GRM5 (0.38) | MAPTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1765795-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | Addex Pharmaceuticals SA (CH) | 2007-03-28 | — | — | EP | disclosed |
| WO-2005123703-A2 | ALKYNYL DERIVATIVES AS MODULATORS OF METABOTROPIC GLUTAMATE RECEPTORS | ADDEX PHARMACEUTICALS SA (CH) | 2005-12-29 | — | — | WO | disclosed |