SCHEMBL5369872

SCHEMBL5369872

CC(C)C[C@H](N)C(=O)N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.77

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 13/20 0.77
ACE P12821 2/20 0.72
ERAP2 Q6P179 2/20 0.68
ALOX15 P16050 1/20 0.64
ANPEP P15144 1/20 0.63
ERAP1 Q9NZ08 1/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29448679 1.00 ECE1 (0.77) ECE1ACEERAP2ALOX15ANPEP
SCHEMBL29435426 1.00 ECE1 (0.77) ECE1ACEERAP2ALOX15ANPEP
SCHEMBL14940856 1.00 ECE1 (0.77) ECE1ACEERAP2ALOX15ANPEP
SCHEMBL29531224 1.00 ECE1 (0.77) ECE1ACEERAP2ALOX15ANPEP
SCHEMBL11589639 1.00 ECE1 (0.77) ECE1ACEERAP2ALOX15ANPEP
SCHEMBL30051190 0.98 ECE1 (0.74) ECE1ACEERAP2ALOX15ANPEP
SCHEMBL30051690 0.97 ERAP2 (0.73) ECE1ACEERAP2ANPEPERAP1
SCHEMBL30051952 0.96 ECE1 (0.71) ECE1ACEERAP2ALOX15ANPEP
SCHEMBL30946945 0.95 ECE1 (0.70) ECE1ACEERAP2ANPEPERAP1
SCHEMBL31564765 0.95 ECE1 (0.69) ECE1ACEERAP2ERAP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4085207-A AND AT LEAST ONE OF N-ACYL-L-TRYPTOPHANS AND N-ACYL-L-PROLINES OTSUKA PHARMACEUTICAL FACTORY, INC. (JA) 1978-04-18 US claimed
EP-3604503-B1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO KK (JP) 2026-03-18 EP disclosed
US-20250270512-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2025-08-28 US disclosed
CN-117310025-A Method for screening key metabolites and pathways of ketosis based on double-platform metabolome 宁夏大学 2023-12-29 CN disclosed
CN-110494559-B Culture medium additive for non-differentiation maintenance 味之素株式会社 2023-10-31 CN disclosed
WO-2020071258-A1 PROTEIN GLYCATION SUPPRESSANT 味の素株式会社 2020-04-09 WO disclosed
US-20200040308-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM AJINOMOTO CO., INC. (JP) 2020-02-06 US disclosed
EP-3604503-A1 ADDITIVE FOR UNDIFFERENTIATION MAINTAINING MEDIUM Ajinomoto Co., Inc. (JP) 2020-02-05 EP disclosed
WO-2016003893-A1 DETECTION OF COLORECTAL CANCER WITH TWO NOVEL HEME-RELATED MOLECULES IN HUMAN FECES THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) 2016-01-07 WO disclosed
US-20140343865-A1 Biomarkers for Kidney Cancer and Methods Using the Same METABOLON, INC. 2014-11-20 US disclosed
US-5608078-A Phosphonomethyldipeptides and process for preparation thereof MERRELL PHARMACEUTICALS INC. (US) 1997-03-04 US disclosed
EP-0691985-A1 PHOSPHONOMETHYLDIPEPTIDES MERRELL PHARMACEUTICALS INC. (US) 1996-01-17 EP disclosed
WO-1994022908-A1 PHOSPHONOMETHYLDIPEPTIDES MERRELL DOW PHARMACEUTICALS INC. (US) 1994-10-13 WO disclosed
EP-0618224-A1 Phosphonomethyldipeptides MERRELL DOW PHARMACEUTICALS INC. (US) 1994-10-05 EP disclosed
US-5036052-A Containing a dipeptide of tryptophan and alanine or lecine and no stabilizer; discoloration inhibition MORISHITA PHARMACEUTICAL CO., LTD. (JP) 1991-07-30 US disclosed
EP-0347890-A1 Amino acid nutrient compositions Roussel Morishita Co., Ltd. (JP) 1989-12-27 EP disclosed
US-4472380-A CARBOXYALKYL DIPEPTIDE DERIVATIVES MERCK & CO., INC. (US) 1984-09-18 US disclosed
US-4374829-A Aminoacid derivatives as antihypertensives MERCK & CO., INC. (US) 1983-02-22 US disclosed
EP-0012401-A1 Carboxyalkyl dipeptide derivatives, process for preparing them and pharmaceutical composition containing them MERCK & CO. INC. (US) 1980-06-25 EP disclosed
US-4085207-A AND AT LEAST ONE OF N-ACYL-L-TRYPTOPHANS AND N-ACYL-L-PROLINES OTSUKA PHARMACEUTICAL FACTORY, INC. (JA) 1978-04-18 US disclosed