Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TLR2 | O60603 | 3/20 | 0.39 |
| ▸ | TLR1 | Q15399 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.39 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.39 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 2/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30532195 | 0.96 | KMT2A (0.66) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL30532196 | 0.96 | KMT2A (0.66) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL84331 | 0.96 | KMT2A (0.66) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL20529972 | 0.96 | KMT2A (0.66) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL31603929 | 0.94 | KMT2A (0.56) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL30905361 | 0.94 | KMT2A (0.56) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL15692103 | 0.94 | KMT2A (0.56) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL31310023 | 0.89 | KMT2A (0.51) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL83644 | 0.89 | KMT2A (0.51) | KMT2AEPHX2TLR2TLR1OPRD1 | |
| SCHEMBL31309796 | 0.89 | KMT2A (0.51) | KMT2AEPHX2TLR2TLR1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | CARMOT THERAPEUTICS, INC. | 2023-11-09 | — | — | US | disclosed |
| US-20170073468-A1 | METHOD FOR PREPARING FUNCTIONALIZED POLYMERS FROM POLYMER ALCOHOLS | NEKTAR THERAPEUTICS | 2017-03-16 | — | — | US | disclosed |
| US-20140073802-A1 | MALEIMIDYL POLYMER DERIVATIVES | NEKTAR THERAPEUTICS (US) | 2014-03-13 | — | — | US | disclosed |
| US-RE39606-E1 | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries | NEXUS BIOSYSTEMS, INC. (US) | 2007-05-01 | — | — | US | disclosed |
| US-RE39571-E1 | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries | NEXUS BIOSYSTEMS, INC. (US) | 2007-04-17 | — | — | US | disclosed |
| US-RE39545-E1 | Methods and apparatus for synthesizing labeled combinatorial chemistry libraries | NEXUS BIOSYSTEMS, INC. (US) | 2007-04-03 | — | — | US | disclosed |
| US-6417010-B1 | SYNTHESIS SUPPORT WITH LABEL | DISCOVERY PARTNERS INTERNATIONAL | 2002-07-09 | — | — | US | disclosed |
| US-6087186-A | SYNTHETIC LIBRARY OF RANDOM OLIGOMERS, EACH MEMBER COMPRISING AN OLIGOMER LINKED TO A MICROCHIP ENCODED WITH INFORMATION IDENTIFYING STRUCTURE OF OLIGOMER; FOR DRUG SCREENING | IRORI (US) | 2000-07-11 | — | — | US | disclosed |
| US-5770455-A | IDENTIFIER TAG WHICH IS A MICROCHIP THAT IS PRE-ENCODED OR ENCODABLE WITH INFORMATION THAT IS RELATED BACK TO A DETECTOR WHEN THE TAG IS PULSED WITH ELECTROMAGNETIC RADIATION | ONTOGEN CORPORATION (US) | 1998-06-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357347-A1 | MODULATORS OF G-PROTEIN COUPLED RECEPTORS | GIPR, GLP1R, GCGR | KMT2A 3040/4885EPHX2 2665/4885TLR2 2228/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.