Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER3 | P43115 | 15/20 | 0.55 |
| ▸ | PTGFR | P43088 | 6/20 | 0.55 |
| ▸ | PTGER2 | P43116 | 3/20 | 0.48 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.48 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.48 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.47 |
| ▸ | LTB4R | Q15722 | 2/20 | 0.45 |
| ▸ | LTB4R2 | Q9NPC1 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGIR | P43119 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5370672 | 1.00 | PTGER3 (0.55) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138027 | 0.87 | PTGER3 (0.69) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138028 | 0.87 | PTGER3 (0.69) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138066 | 0.79 | PTGER3 (0.64) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138069 | 0.79 | PTGER3 (0.64) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138079 | 0.78 | PTGER3 (0.68) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138083 | 0.78 | PTGER3 (0.68) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138041 | 0.77 | PTGER3 (0.65) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1138046 | 0.77 | PTGER3 (0.65) | PTGER3PTGFRPTGER2PTGER4PTGER1 | |
| SCHEMBL1137616 | 0.74 | PTGER3 (0.68) | PTGER3PTGFRPTGER2PTGER4PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1814881-A2 | CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE | Decode Genetics, Inc. (US) | 2007-08-08 | — | — | EP | disclosed |
| WO-2006044415-A2 | CARBOXYLIC ACID PERI - SUBSTITUTED BICYCLICS FOR OCCLUSIVE ARTERY DISEASE | DECODE GENETICS, INC. (US) | 2006-04-27 | — | — | WO | disclosed |