SCHEMBL537129

SCHEMBL537129

CC(C)C(NC(=O)C(N)CCC(=O)O)C(=O)O

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 2/20 0.61
DPP8 Q6V1X1 2/20 0.61
DPP9 Q86TI2 2/20 0.61
CYP1A2 P05177 2/20 0.52
GRM8 O00222 1/20 0.52
GRM6 O15303 1/20 0.52
GRIN2D O15399 1/20 0.52
GRIN3B O60391 1/20 0.52
GSR P00390 1/20 0.52
GRIK1 P39086 1/20 0.52
GRM5 P41594 1/20 0.52
GRIA1 P42261 1/20 0.52
GRIA2 P42262 1/20 0.52
GRIA3 P42263 1/20 0.52
SLC1A3 P43003 1/20 0.52
SLC1A2 P43004 1/20 0.52
SLC1A1 P43005 1/20 0.52
GRIA4 P48058 1/20 0.52
GRIN1 Q05586 1/20 0.52
GRIN2A Q12879 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL537127 1.00 DPP4 (0.61) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL29531533 1.00 DPP4 (0.61) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL29531781 0.97 DPP4 (0.58) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL29865375 0.94 DPP4 (0.55) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL30997439 0.92 DPP4 (0.54) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL6386178 0.92 DPP4 (0.54) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL18797432 0.92 DPP4 (0.54) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL31571451 0.91 BACE1 (0.53) DPP4DPP8DPP9CYP1A2GRM8
SCHEMBL31181278 0.91 BACE1 (0.53) DPP4DPP8DPP9BACE1CTSD
SCHEMBL30483835 0.90 BACE1 (0.54) DPP4DPP8DPP9BACE1CTSD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 88 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118897023-B Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2025-03-25 CN claimed
CN-118897023-A Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2024-11-05 CN claimed
US-20190120855-A1 Biomarkers for Fatty Liver Disease and Methods Using the Same THE CLEVELAND CLINIC FOUNDATION 2019-04-25 US claimed
US-9977034-B2 Biomarkers for fatty liver disease and methods using the same Meabolon, Inc. (US) 2018-05-22 US claimed
US-20150377910-A1 Biomarkers for Fatty Liver Disease and Methods Using the Same METABOLON, INC. 2015-12-31 US claimed
US-20150065460-A1 Biomarkers Related to Insulin Resistance and Methods Using the Same METABOLON, INC. 2015-03-05 US claimed
EP-2546649-B1 Biomarkers for fatty liver disease and methods using the same METABOLON INC (US) 2015-02-25 EP claimed
EP-2756095-A1 BIOMARKERS RELATED TO INSULIN RESISTANCE AND METHODS USING THE SAME Metabolon, Inc. (US) 2014-07-23 EP claimed
WO-2013039898-A1 BIOMARKERS RELATED TO INSULIN RESISTANCE AND METHODS USING THE SAME METABOLON, INC. (US) 2013-03-21 WO claimed
EP-2546649-A2 Biomarkers for fatty liver disease and methods using the same Metabolon Inc. (US) 2013-01-16 EP claimed
EP-2227689-B1 BIOMARKERS FOR FATTY LIVER DISEASE AND METHODS USING THE SAME METABOLON INC (US) 2012-12-26 EP claimed
US-20120122981-A1 Biomarkers Related to Insulin Resistance and Methods using the Same METABOLON, INC. 2012-05-17 US claimed
EP-2414535-A1 BIOMARKERS RELATED TO INSULIN RESISTANCE AND METHODS USING THE SAME Metabolon Inc. (US) 2012-02-08 EP claimed
US-20100279956-A1 Biomarkers For Fatty Liver Disease And Methods Using The Same METABOLON, INC. 2010-11-04 US claimed
WO-2010114897-A1 BIOMARKERS RELATED TO INSULIN RESISTANCE AND METHODS USING THE SAME METABOLON, INC. (US) 2010-10-07 WO claimed
CN-120189526-A Hoberthidiene antibody-drug conjugates and methods of use 卫材R&D管理有限公司 2025-06-24 CN disclosed
CN-118897023-B Method for directly measuring alpha and gamma-glutamyl peptide in skeletal muscle by using LC-MS and isotope dilution assay 中国农业科学院北京畜牧兽医研究所 2025-03-25 CN disclosed
US-20090169704-A1 Process for the enzymatic preparation of a gamma-glutamyl compound CONOPCO, INC. D/B/A UNILEVER 2009-07-02 US disclosed
US-20080305151-A1 Dipeptide-Comprising Composition for Oral Administration KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-12-11 US disclosed
EP-1941896-A1 DIPEPTIDE-CONTAINING COMPOSITION FOR ORAL ADMINISTRATION KYOWA HAKKO KOGYO CO., LTD. (JP) 2008-07-09 EP disclosed