SCHEMBL537187

SCHEMBL537187

C=CCN1C(=O)N(C)C2(CC(C)(C)NC(C)(C)C2)C1=O

nearest known ligand 0.37

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
POLB P06746 1/20 0.37
GAA P10253 2/20 0.36
TSHR P16473 1/20 0.32
MAPT P10636 2/20 0.32
L3MBTL1 Q9Y468 1/20 0.32
CNR1 P21554 1/20 0.31
MEN1 O00255 1/20 0.30
CYP1A2 P05177 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11081294 0.84 POLB (0.35) POLBGAATSHRL3MBTL1
SCHEMBL13597773 0.81 POLB (0.33) POLBGAATSHRL3MBTL1
SCHEMBL13597776 0.81 POLB (0.33) POLBGAATSHRL3MBTL1
SCHEMBL11288176 0.76 GAA (0.33) POLBGAATSHRL3MBTL1
SCHEMBL4841706 0.76 GAA (0.45) POLBGAATSHRMAPTL3MBTL1
SCHEMBL8462528 0.73 POLB (0.60) POLBGAATSHRMAPTL3MBTL1
SCHEMBL11478688 0.71
SCHEMBL27096133 0.68 GAA (0.42) POLBGAATSHRMAPTL3MBTL1
SCHEMBL15974512 0.67 POLB (0.39) POLBGAATSHRMAPTL3MBTL1
SCHEMBL11221046 0.64 GAA (0.44) POLBGAATSHRMAPTL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3365380-B1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-04-26 EP disclosed
US-11542389-B2 Vinyl chloride polymers and compositions for additive manufacturing AKDENIZ CHEMSON ADDITIVES AG (AT) 2023-01-03 US disclosed
US-20210017374-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2021-01-21 US disclosed
US-10829629-B2 Vinyl chloride polymers and compositions for additive manufacturing CHEMSON POLYMER-ADDITIVE AG (AT) 2020-11-10 US disclosed
WO-2020058337-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS BOREALIS AG (AT) 2020-03-26 WO disclosed
EP-3626772-A1 USE OF A MELAMINE BASED COMPOUND AND A HALS COMPOUND AS HEAT STABILIZER IN POLYMERS Borealis AG (AT) 2020-03-25 EP disclosed
US-20180305536-A1 VINYL CHLORIDE POLYMERS AND COMPOSITIONS FOR ADDITIVE MANUFACTURING AKDENIZ CHEMSON ADDITIVES AG (AT) 2018-10-25 US disclosed
US-9951205-B2 Stable compositions of thiabendazole and iodine-containing fungicides LANXESS DEUTSCHLAND GMBH (DE) 2018-04-24 US disclosed
EP-2758462-B1 STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS BOREALIS AG (AT) 2018-03-07 EP disclosed
EP-2413697-B1 STABILISATION OF COMPOUNDS CONTAINING IODINE LANXESS DEUTSCHLAND GMBH (DE) 2017-11-08 EP disclosed
EP-0083308-A1 Process for stabilising fungicides CIBA-GEIGY AG (CH) 1983-07-06 EP disclosed
EP-0015230-B1 STABILIZED ORGANIC POLYMER COMPRISING 2-(2-HYDROXY-3,5-DI-TERT-OCTYLPHENYL)-2H-BENZOTRIAZOLE AS A LIGHT-STABILIZER CIBA-GEIGY AG (CH) 1983-02-23 EP disclosed
US-4315848-A PROTECTIVE COATING FOR AUTOMOBILES CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
US-4314933-A 2,2,6,6-TETRAALKYLPIPERIDINE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1982-02-09 US disclosed
US-4278589-A 2-[2-Hydroxy-3,5-di-(α,α-dimethylbenzyl)phenyl]-2H-benzotriazole and stabilized compositions CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
US-4278590-A AUTOMOBILE FINISHES CIBA-GEIGY CORPORATION (US) 1981-07-14 US disclosed
EP-0016723-A1 Light stabilisation of two-layer composite lacquers CIBA-GEIGY AG (CH) 1980-10-01 EP disclosed
EP-0015230-A1 Stabilized organic Polymer comprising 2-(2-hydroxy-3,5-di-tert-octylphenyl)-2H-benzotriazole as a light-stabilizer CIBA-GEIGY AG (CH) 1980-09-03 EP disclosed
EP-0006564-A2 2-(3.5-disubstituted-2-hydroxyphenyl)-2H-benzotriazoles and stabilized compositions containing them CIBA-GEIGY AG (CH) 1980-01-09 EP disclosed
EP-0002753-A2 Stabilisation of heat-curable metallic enamel paints against the action of light, humidity and oxygen by the addition of polyalkylpiperidine derivatives CIBA-GEIGY AG (CH) 1979-07-11 EP disclosed