Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 15/20 | 0.48 |
| ▸ | PPARA | Q07869 | 14/20 | 0.48 |
| ▸ | KDR | P35968 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6594785 | 0.92 | FFAR1 (0.54) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6594791 | 0.92 | FFAR1 (0.54) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL5387806 | 0.92 | FFAR1 (0.55) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL5376753 | 0.87 | FFAR1 (0.52) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL5384912 | 0.87 | FFAR1 (0.53) | FFAR1PPARGPPARAKDR | |
| SCHEMBL5372006 | 0.86 | FFAR1 (0.51) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL5381850 | 0.86 | FFAR1 (0.54) | FFAR1PPARGPPARA | |
| SCHEMBL5374673 | 0.84 | FFAR1 (0.59) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL5374677 | 0.84 | FFAR1 (0.59) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL5381909 | 0.82 | FFAR1 (0.52) | FFAR1PPARGPPARAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |