Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 17/20 | 0.47 |
| ▸ | CTSD | P07339 | 12/20 | 0.47 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3350296 | 0.92 | BACE1 (0.51) | BACE1CTSDBACE2 | |
| SCHEMBL3354472 | 0.92 | BACE1 (0.47) | BACE1CTSDBACE2TP53 | |
| SCHEMBL3357668 | 0.91 | BACE1 (0.41) | BACE1CTSDBACE2TP53 | |
| SCHEMBL3348410 | 0.90 | BACE1 (0.48) | BACE1CTSDBACE2 | |
| SCHEMBL3347690 | 0.90 | BACE1 (0.55) | BACE1CTSDBACE2 | |
| SCHEMBL3348757 | 0.90 | BACE1 (0.49) | BACE1CTSDBACE2 | |
| SCHEMBL3356802 | 0.90 | BACE1 (0.47) | BACE1CTSDBACE2TP53 | |
| SCHEMBL3357431 | 0.89 | BACE1 (0.45) | BACE1CTSDBACE2 | |
| SCHEMBL3351398 | 0.89 | BACE1 (0.49) | BACE1CTSDBACE2 | |
| SCHEMBL3348456 | 0.88 | BACE1 (0.51) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |