Spermine

Spermine

SCHEMBL5373330

CC(=O)C(C)=O.NCCCNCCCCNCCCN

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PAOX Q6QHF9 3/20 0.69
CA12 O43570 2/20 0.65
F13A1 P00488 2/20 0.65
CA2 P00918 2/20 0.65
CYP1A2 P05177 2/20 0.65
ALOX15 P16050 2/20 0.65
CA4 P22748 2/20 0.65
CA6 P23280 2/20 0.65
CA5A P35218 2/20 0.65
THPO P40225 2/20 0.65
CA7 P43166 2/20 0.65
CA9 Q16790 2/20 0.65
CA14 Q9ULX7 2/20 0.65
CA5B Q9Y2D0 2/20 0.65
CASP2 P42575 2/20 0.65
MEN1 O00255 1/20 0.65
CYP2C19 P33261 1/20 0.65
RECQL P46063 1/20 0.65
KMT2A Q03164 1/20 0.65
HSD17B10 Q99714 1/20 0.65

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Spermidine SCHEMBL8143730 0.98 PAOX (0.67) PAOXCA12F13A1CA2CYP1A2
Spermine SCHEMBL6422290 0.90 PAOX (0.69) PAOXCA12F13A1CA2CYP1A2
Spermine SCHEMBL625285 0.90 PAOX (0.69) PAOXCA12F13A1CA2CYP1A2
Spermine SCHEMBL7261475 0.90 PAOX (0.69) PAOXCA12F13A1CA2CYP1A2
Spermidine SCHEMBL10961981 0.88 PAOX (0.67) PAOXCA12F13A1CA2CYP1A2
Spermidine SCHEMBL2076472 0.88 PAOX (0.67) PAOXCA12F13A1CA2CYP1A2
Spermidine SCHEMBL5615318 0.88 PAOX (0.67) PAOXCA12F13A1CA2CYP1A2
Spermidine SCHEMBL7264809 0.88 PAOX (0.67) PAOXCA12F13A1CA2CYP1A2
Spermine SCHEMBL866361 0.88 PAOX (0.67) PAOXCA12F13A1CA2CYP1A2
Spermine SCHEMBL27858984 0.84 CA12 (0.72) PAOXCA12F13A1CA2CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119968213-A Methods for detecting and treating ovarian cancer 德州大学系统董事会 2025-05-09 CN claimed
EP-4518832-A1 CHONDROITIN- AND COLLAGEN PEPTIDE-BASED METHODS FOR SLOWING DOWN AGING AND EXTENDING LIFESPAN Ageless Sciences, Inc. (US) 2025-03-12 EP claimed
CN-119173247-A Methods for slowing aging and prolonging life based on chondroitin and collagen peptides 不老科学公司 2024-12-20 CN claimed
CN-117820489-B Antibody fusion protein and preparation method and application thereof 顾达鸣 2024-09-27 CN claimed
CN-117915926-A Serometabonomics associated with Chimeric Antigen Receptor (CAR) T cell therapy 得克萨斯州大学系统董事会 2024-04-19 CN claimed
CN-117820489-A Antibody fusion protein and preparation method and application thereof 广州杰博生物科技有限公司 2024-04-05 CN claimed
WO-2023215454-A1 CHONDROITIN- AND COLLAGEN PEPTIDE-BASED METHODS FOR SLOWING DOWN AGING AND EXTENDING LIFESPAN AGELESS SCIENCES, INC. (US) 2023-11-09 WO claimed
CN-116601488-A Method and consumer product for detecting metabolites 金伯利-克拉克环球有限公司 2023-08-15 CN claimed
CN-116529603-A Methods for detecting and treating lung cancer 德州大学系统董事会 2023-08-01 CN claimed
CN-116490776-A Methods for detecting and treating ovarian cancer 德州大学系统董事会 2023-07-25 CN claimed
CN-109870579-A Monoclonal antibody protects liquid and preparation method and application, using the reagent and immunohistochemical kit of monoclonal antibody protection liquid 辽宁迈迪生物科技股份有限公司 2019-06-11 CN claimed
US-20190033313-A1 METHODS AND SYSTEMS FOR DETECTING MELANOMA UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2019-01-31 US claimed
WO-2018112428-A1 METHODS FOR THE DETECTION AND TREATMENT OF PANCREATIC DUCTAL ADENOCARCINOMA BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM (US) 2018-06-21 WO claimed
CN-108139381-A Lung cancer detection method 百奥马克癌症系统公司 2018-06-08 CN claimed
CN-105527434-B One kind is used for the kit of diacetyl spermine (DAS) detection 辽宁迈迪生物科技有限公司 2017-12-19 CN claimed
CN-107300613-A A kind of biomarker, the method for sampling, modeling method and application thereof 深圳市优圣康生物科技有限公司 2017-10-27 CN claimed
CN-104316685-B Diacetyl spermine detection kit and preparation method and application thereof 辽宁迈迪生物科技有限公司 2017-04-12 CN claimed
WO-2016196743-A1 METHODS AND SYSTEMS FOR DETECTING MELANOMA THE UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2016-12-08 WO claimed
CN-105527434-A A kit used for detecting N1,N<12>-diacetylspermine (DAS) LIAONING MAIDI BIOTECHNOLOGY CO LTD 2016-04-27 CN claimed
CN-104316685-A Diacetyl spermine detection kit and preparation method and application thereof LIAONING MAIDI BIOTECHNOLOGY CO LTD 2015-01-28 CN claimed