Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 15/20 | 0.43 |
| ▸ | CTSD | P07339 | 10/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377821 | 0.95 | BACE1 (0.42) | BACE1CTSDTP53 | |
| SCHEMBL3352279 | 0.92 | BACE1 (0.47) | BACE1CTSDTP53 | |
| SCHEMBL3356453 | 0.91 | BACE1 (0.42) | BACE1CTSDTP53 | |
| SCHEMBL3354577 | 0.90 | BACE1 (0.46) | BACE1CTSD | |
| SCHEMBL3356990 | 0.89 | BACE1 (0.46) | BACE1CTSDTP53 | |
| SCHEMBL3348724 | 0.88 | BACE1 (0.43) | BACE1CTSDTP53 | |
| SCHEMBL3354723 | 0.87 | BACE1 (0.43) | BACE1CTSDTP53 | |
| SCHEMBL3354445 | 0.87 | BACE1 (0.42) | BACE1CTSDTP53 | |
| SCHEMBL3351214 | 0.86 | BACE1 (0.42) | BACE1CTSDTP53 | |
| SCHEMBL3349879 | 0.86 | BACE1 (0.42) | BACE1CTSDTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |