Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 2/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.36 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.36 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.36 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 3/20 | 0.36 |
| ▸ | NTRK1 | P04629 | 2/20 | 0.36 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | PLK4 | O00444 | 1/20 | 0.36 |
| ▸ | DCLK1 | O15075 | 1/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.36 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.36 |
| ▸ | DYRK3 | O43781 | 1/20 | 0.36 |
| ▸ | JAK2 | O60674 | 1/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.36 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5387119 | 0.88 | CSNK1D (0.45) | CSNK1DMAPK1DYRK1ANTRK1CDC7 | |
| SCHEMBL5393207 | 0.84 | CSNK1D (0.47) | CSNK1DMAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL5383779 | 0.83 | CSNK1D (0.43) | CSNK1DS1PR1MAPK1MAP2K4DYRK1A | |
| SCHEMBL5378626 | 0.83 | CSNK1D (0.48) | CSNK1DS1PR1MAPK1MAP2K4MAPKAPK2 | |
| SCHEMBL5378295 | 0.83 | CSNK1D (0.51) | CSNK1DMAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL5372967 | 0.82 | CSNK1D (0.64) | CSNK1DMAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL5377949 | 0.81 | CSNK1D (0.54) | CSNK1DMAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL5372338 | 0.81 | CSNK1D (0.49) | CSNK1DMAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL5383966 | 0.81 | CSNK1D (0.49) | CSNK1DMAPK1MAP2K4MAPKAPK2MAPKAPK3 | |
| SCHEMBL5387313 | 0.81 | CSNK1D (0.52) | CSNK1DMAP2K4DYRK1ANTRK1CLK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7211594-B2 | Indazole compounds and compositions thereof as JNK inhibitors and for the treatment of diseases associated therewith | SIGNAL PHARMACEUTICALS, LLC (US) | 2007-05-01 | — | — | US | claimed |
| US-20040127536-A1 | Methods for treating an inflammatory condition or inhibiting JNK | SIGNAL PHARMACEUTICALS, LLC | 2004-07-01 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040127536-A1 | Methods for treating an inflammatory condition or inhibiting JNK | MAPK1, MAP3K1, MAPKAPK2 | CSNK1D 349/4885S1PR1 725/4885MAPK1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.