SCHEMBL537368

SCHEMBL537368

Cn1nc(Cl)cc1O

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23812322 0.74
SCHEMBL1305126 0.72
SCHEMBL420240 0.72
SCHEMBL12569915 0.70
SCHEMBL21737385 0.70
SCHEMBL1914965 0.70
SCHEMBL1305124 0.70
SCHEMBL31261225 0.70
SCHEMBL1716280 0.69 MAPT (0.50)
SCHEMBL3058674 0.69 KDM4E (0.39)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4459294-A MITICIDES, NEMATOCIDES MONTEDISON S.P.A. (IT) 1984-07-10 US claimed
EP-1767528-B1 PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND IHARA CHEMICAL IND CO (JP) 2014-09-17 EP disclosed
CN-1938278-B Process for producing 5-hydroxy-4-thiomethylpyrazole compound IHARA CHEMICAL IND CO 2012-12-12 CN disclosed
CN-102659683-A Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound IHARA CHEMICAL IND CO 2012-09-12 CN disclosed
CN-101384556-B Process for producing 5-alkoxy-4-hydroxymethylpyrazole compound IHARA CHEMICAL IND CO 2012-06-20 CN disclosed
EP-1990336-B1 PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND IHARA CHEMICAL IND CO (JP) 2012-02-08 EP disclosed
US-7812175-B2 Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound IHARA CHEMICAL INDUSTRY CO., LTD. (JP) 2010-10-12 US disclosed
US-7635664-B2 Herbicidal substituted benzoylpyrazoles BAYER CROPSCIENCE AG (DE) 2009-12-22 US disclosed
US-7635664-B2 Herbicidal substituted benzoylpyrazoles BAYER CROPSCIENCE AG (DE) 2009-12-22 US disclosed
US-7635664-B2 Herbicidal substituted benzoylpyrazoles BAYER CROPSCIENCE AG (DE) 2009-12-22 US disclosed
EP-1767528-A1 PROCESS FOR PRODUCING 5-HYDROXY-4-THIOMETHYLPYRAZOLE COMPOUND IHARA CHEMICAL INDUSTRY Co., Ltd. (JP) 2007-03-28 EP disclosed
CN-1938278-A Process for producing 5-hydroxy-4-thiomethylpyrazole compound IHARA CHEMICAL IND CO (JP) 2007-03-28 CN disclosed
CN-1256329-C Herbicidally active substituted benzoylpyrazoles BAYER CROPS SCIENCE AG (DE) 2006-05-17 CN disclosed
US-20040248740-A1 Substituted benzoylpyrazoles MULLER KLAUS-HELMUT (DE) 2004-12-09 US disclosed
CN-1511143-A Herbicidally active substituted benzoylpyrazoles 拜尔农作物科学股份公司 2004-07-07 CN disclosed
US-20040110640-A1 Herbicidal substituted benzoylpyrazoles BAYER CROPSCIENCE AG (DE) 2004-06-10 US disclosed
US-6746989-B1 HAVE STRONG HERBICIDAL ACTIVITY AND BROAD ACTIVITY SPECTRUM WHEN APPLIED TO SOIL AND ON ABOVE-GROUND PARTS OF PLANTS BAYER AKTIENGESELLSCHAFT (DE) 2004-06-08 US disclosed
CN-1146560-C Substituted benzoylpyrazoles as herbicides 2004-04-21 CN disclosed
EP-1165547-B1 SUBSTITUTED BENZOYLPYRAZOLES AS HERBICIDES BAYER CROPSCIENCE AG (DE) 2003-08-27 EP disclosed
CN-1346354-A Substituted benzoylpyrazoles as herbicides BAYER AG (DE) 2002-04-24 CN disclosed