SCHEMBL537409

SCHEMBL537409

CC(C)(C)CCI

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11405081 0.77
SCHEMBL3521772 0.75
SCHEMBL25479035 0.72
SCHEMBL14404994 0.72
SCHEMBL31190173 0.72
SCHEMBL598853 0.71 TSHR (0.46)
SCHEMBL6275726 0.69
SCHEMBL798865 0.69
SCHEMBL5908680 0.69
SCHEMBL6889067 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100378054-C Preparation method of 3, 3-dimethylbutyraldehyde NUTRASWEET CO (US) 2008-04-02 CN claimed
US-7348459-B2 Reacting isobutylene, ethylene and mineral acid; hydrolyzing the ester to produce 3,3-dimethylbutanol, and converting 3,3-dimethylbutanol to 3,3-dimethylbutanal; by-product inhibition THE NUTRASWEET COMPANY (US) 2008-03-25 US claimed
US-20070106086-A1 Reacting isobutylene, ethylene and mineral acid; hydrolyzing the ester to produce 3,3-dimethylbutanol, and converting 3,3-dimethylbutanol to 3,3-dimethylbutanal; by-product inhibition THE NUTRASWEET COMPANY (US) 2007-05-10 US claimed
US-20040006247-A1 Reacting isobutylene, ethylene and mineral acid; hydrolyzing the ester to produce 3,3-dimethylbutanol; and converting 3,3-dimethylbutanol to 3,3-dimethylbutanal THE NUTRASWEET COMPANY 2004-01-08 US claimed
US-20030229254-A1 Reacting isobutylene, ethylene and mineral acid;hydrolysis of corresponding ester to alcohol; catalytic dehydrogenation THE NUTRASWEET COMPANY 2003-12-11 US claimed
WO-2025129104-A1 COMPOUNDS, COMPOSITIONS, AND METHODS OF USING THEREOF SIONNA THERAPEUTICS INC. (US) 2025-06-19 WO disclosed
EP-3340988-B1 ION CHANNEL INHIBITORY COMPOUNDS, PHARMACEUTICAL FORMULATIONS AND USES AFASCI INC (US) 2025-04-09 EP disclosed
CN-114174354-B Process for producing modified conjugated diene polymer 株式会社LG化学 2024-10-01 CN disclosed
US-20240002374-A1 5-MEMBERED HETEROARYLAMINOSULFONAMIDES FOR TREATING CONDITIONS MEDIATED BY DEFICIENT CFTR ACTIVITY GENZYME CORPORATION 2024-01-04 US disclosed
EP-4058439-A1 5-MEMBERED HETEROARYLAMINOSULFONAMIDES FOR TREATING CONDITIONS MEDIATED BY DEFICIENT CFTR ACTIVITY Genzyme Corporation (US) 2022-09-21 EP disclosed
CN-115003659-A 5-membered heteroaryl amino sulfonamides for the treatment of conditions mediated by a deficiency in CFTR activity 健赞公司 2022-09-02 CN disclosed
CN-108289886-B Ion channel inhibiting compounds, pharmaceutical formulations and uses 安华赛公司 2022-01-28 CN disclosed
US-20050107364-A1 Viricides for infections caused by an RNA-containing virus; enzyme inhibitors for a hepatitis C virus (HCV) polymerase; inhibiting HCV viral replication; liver cirrhosis; e. g., 3-(1,1-dioxido-4H-1,2,4-benzothiadiazin-3-yl)-4-hydroxy-1,1-dipropyl-2(1H)-naphthalenone ABBVIE INC. 2005-05-19 US disclosed
WO-2005019191-A2 1, 1-DIOXIDO-4H-1,2,4-BENZOTHIADIAZINE DERIVATE UND VERWANDTE VERBINDUNGEN ALS INHIBITOREN DER HCV POLYMERASE ZUR BEHANDLUNG VON HEPATITIS C ABBOTT LABORATORIES (US) 2005-03-03 WO disclosed
US-6448282-B1 H3 HISTAMINE RECEPTOR ANTAGONIST ACTIVITY; ALLERGY, INFLAMMATION, CARDIOVASCULAR DISEASE, DEPRESSION, SCHIZOPHRENIA, NARCOLEPSY, SLEEP APNEA, INSOMNIA, EPILEPSY, HYPOTHALAMIC DYSFUNCTION GLIATECH, INC. 2002-09-10 US disclosed
US-6166060-A 1H-4(5)-substituted imidazole derivatives GLIATECH, INC. (US) 2000-12-26 US disclosed
US-6008240-A AN ANTAGONIST OF HISTAMINE H3 RECEPTORS; FOR TREATING ALLERGY, INFLAMMATION, CARDIOVASCULAR DISEASE (HYPER OR HYPOTENSION), GASTROINTESTINAL DISORDERS, CNS DISORDERS INVOLVING ATTENTION OR COGNITIVE DISORDERS GLIATECH, INC. (US) 1999-12-28 US disclosed
EP-0563104-A1 PESTICIDAL COMPOUNDS ROUSSEL UCLAF (FR) 1993-10-06 EP disclosed
WO-1992011253-A1 PESTICIDAL COMPOUNDS ROUSSEL UCLAF (FR) 1992-07-09 WO disclosed
US-5026874-A Agricultural insecticides WELLCOME FOUNDATION LIMITED (GB) 1991-06-25 US disclosed