Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP14 | P50281 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ANPEP | P15144 | 1/20 | 0.32 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27646674 | 0.91 | EPHX2 (0.47) | EPHX2TSHRCYP3A4ATMTDP1 | |
| SCHEMBL5373514 | 0.90 | EPHX2 (0.47) | EPHX2TSHRCYP3A4ATMTDP1 | |
| SCHEMBL27626191 | 0.88 | EPHX2 (0.45) | EPHX2TSHRCYP3A4ATMTDP1 | |
| SCHEMBL5371363 | 0.87 | EPHX2 (0.47) | EPHX2S1PR5 | |
| SCHEMBL9107859 | 0.86 | EPHX2 (0.47) | EPHX2ANPEPBTKS1PR5 | |
| SCHEMBL5375229 | 0.85 | EPHX2 (0.46) | EPHX2ANPEPBTKS1PR5 | |
| SCHEMBL5372110 | 0.85 | EPHX2 (0.45) | EPHX2S1PR5 | |
| SCHEMBL5363251 | 0.85 | EPHX2 (0.45) | EPHX2S1PR5 | |
| SCHEMBL5362953 | 0.85 | EPHX2 (0.45) | EPHX2S1PR5 | |
| SCHEMBL27646579 | 0.85 | EPHX2 (0.45) | EPHX2S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7208545-B1 | Selected cyclohexane -1,3-and -1,4-dicarboxylic acid esters | BASF AKTIENGESELLSCHAFT (DE) | 2007-04-24 | — | — | US | claimed |