Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.54 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.35 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.35 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28312759 | 1.00 | CYP1A2 (0.54) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL20415293 | 0.98 | CYP1A2 (0.50) | CYP1A2CYP2D6MAPTCYP2C9CYP2C19 | |
| SCHEMBL16499782 | 0.91 | — | — | |
| SCHEMBL476298 | 0.81 | — | — | |
| SCHEMBL28569684 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1APRMT1 | |
| SCHEMBL453216 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1APRMT1 | |
| SCHEMBL2029681 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1APRMT1 | |
| SCHEMBL20836564 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1APRMT1 | |
| SCHEMBL30541972 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1APRMT1 | |
| SCHEMBL15871737 | 0.81 | KDM4E (0.55) | ALDH1A1KDM4EMAPK1HIF1APRMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0938470-B1 | AQUEOUS SYNTHESIS OF IODOPROPARGYL CARBAMATE | TROY TECHNOLOGY CORP INC (US) | 2001-09-26 | — | — | EP | claimed |
| EP-4334307-A1 | CDK2 DEGRADERS AND USES THEREOF | Kymera Therapeutics, Inc. (US) | 2024-03-13 | — | — | EP | disclosed |
| WO-2022236058-A1 | CDK2 DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |
| EP-2473481-A1 | PROCESS FOR PREPARING IODOPROPARGYL COMPOUNDS | Lanxess Deutschland GmbH (DE) | 2012-07-11 | — | — | EP | disclosed |
| EP-2289873-B1 | Process for the preparation of iodopropargyl compounds | LANXESS DEUTSCHLAND GMBH (DE) | 2012-02-08 | — | — | EP | disclosed |
| WO-2011023757-A1 | PROCESS FOR PREPARING IODOPROPARGYL COMPOUNDS | LANXESS DEUTSCHLAND GMBH (DE) | 2011-03-03 | — | — | WO | disclosed |
| EP-2289873-A1 | Process for the preparation of iodopropargyl compounds | LANXESS Deutschland GmbH (DE) | 2011-03-02 | — | — | EP | disclosed |