SCHEMBL537495

SCHEMBL537495

O=C(O)C1=COC=CO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL27782796 0.98
SCHEMBL30196030 0.98
Formaldehyde SCHEMBL27842049 0.95
SCHEMBL9653572 0.95
SCHEMBL12077228 0.86
SCHEMBL693912 0.78
SCHEMBL83826 0.78
SCHEMBL30647272 0.78
SCHEMBL27829425 0.77
SCHEMBL9653578 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 267 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117903367-A Modified starch filtrate reducer for drilling fluid, preparation method thereof and drilling fluid 中国石油化工股份有限公司 2024-04-19 CN claimed
CN-107743483-B NADPH oxidase 4 inhibitors 埃科特莱茵药品有限公司 2022-01-28 CN claimed
CN-110642741-A Functionalized benzamide derivatives as antiviral agents against HBV infection 巴鲁克斯布隆伯格研究所 2020-01-03 CN claimed
CN-110462040-A Regulation of polypeptide expression by novel gene switch expression systems INTREXON CORP 2019-11-15 CN claimed
CN-104918612-B Functionalized benzamide derivatives as antiviral agents against HBV infection 巴鲁克斯布隆伯格研究所 2019-10-25 CN claimed
CN-109232517-A One group of sulphonyl coumarin derivatives and its application in preparation of anti-tumor drugs 郑州大学第附属医院 2019-01-18 CN claimed
WO-2017192304-A1 ARYLCARBOXAMIDES AND USES THEREOF INCEPTION 1, INC. (US) 2017-11-09 WO claimed
CN-104302633-B Benzo [1,3] dioxine derivatives and their use as LPAR5 antagonists 赛诺菲 2016-09-07 CN claimed
EP-2928459-A2 FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION Baruch S. Blumberg Institute (US) 2015-10-14 EP claimed
CN-104918612-A FUNCTIONALIZED BENZAMIDE DERIVATIVES AS ANTIVIRAL AGENTS AGAINST HBV INFECTION INST HEPATITIS & VIRUS RES 2015-09-16 CN claimed
US-20020119977-A1 Substituted aryl compounds as novel cyclooxygenase-2 selective inhibitors, compositions and methods of use related applications NICOX S.A. (FR) 2002-08-29 US claimed
WO-2002060378-A2 SUBSTITUTED ARYL COMPOUNDS AS CYCLOOXYGENASE-2 SELECTIVE INHIBITORS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2002-08-08 WO claimed
CN-1315950-A Dihydrobenzodioxine carboxamide and ketone derivatives as 5-HT 4 receptor antagonists HOFFMANN LA ROCHE (CH) 2001-10-03 CN claimed
EP-1112270-A1 DIHYDROBENZODIOXINE CARBOXAMIDE AND KETONE DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2001-07-04 EP claimed
EP-0904057-B1 LIPOSOME ENCAPSULATED AMPHIPHILIC DRUG COMPOSITIONS UNIV BRUXELLES (BE) 2001-06-20 EP claimed
US-6149937-A SELECTING AMPHIPHILIC COMPOUND IONIC SPECIES OF WHICH WILL PARTLY INSERT INTO LIPOSOMAL PHOSPHOLIPID BILAYERS BY NUMERIC MOLECULAR MODELLING OR CONFORMATIONAL ANALYSIS; EXTRACTING HYDROPHILIC IONIC SPECIES; PREPARING LIPID FILM AND SUSPENSION VRIJE UNIVERSITEIT BRUSSEL (BE) 2000-11-21 US claimed
WO-2000015636-A1 DIHYDROBENZODIOXINE CARBOXAMIDE AND KETONE DERIVATIVES AS 5-HT4 RECEPTOR ANTAGONISTS F. HOFFMANN-LA ROCHE AG (CH) 2000-03-23 WO claimed
EP-0904057-A1 LIPOSOME ENCAPSULATED AMPHIPHILIC DRUG COMPOSITIONS VRIJE UNIVERSITEIT BRUSSEL (BE) 1999-03-31 EP claimed
CN-1205004-A Novel esters of 3-hydroxy-piperidinemethanol derivatives JANSSEN PHARMACEUTICA NV (BE) 1999-01-13 CN claimed
WO-1997034582-A1 LIPOSOME ENCAPSULATED AMPHIPHILIC DRUG COMPOSITIONS VRIJE UNIVERSITEIT BRUSSEL (BE) 1997-09-25 WO claimed