SCHEMBL5375141

SCHEMBL5375141

CCCCCCCCCN1C(=O)c2ccc3c4cccc5cccc(c6ccc(c2c36)C1=O)c54

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 1/20 0.55
HIF1A Q16665 1/20 0.55
HEXA P06865 2/20 0.52
HEXB P07686 2/20 0.52
KMT2A Q03164 5/20 0.52
MEN1 O00255 4/20 0.52
POLB P06746 3/20 0.52
RGS12 O14924 2/20 0.52
HTT P42858 2/20 0.52
USP2 O75604 1/20 0.52
MAPT P10636 1/20 0.52
MAPK1 P28482 1/20 0.52
ATM Q13315 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
TLR9 Q9NR96 1/20 0.52
TDP1 Q9NUW8 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
CYP3A4 P08684 1/20 0.51
NFKB1 P19838 1/20 0.51
HSD17B10 Q99714 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8165344 1.00 STAT3 (0.55) STAT3HIF1AHEXAHEXBKMT2A
SCHEMBL7649614 1.00 STAT3 (0.55) STAT3HIF1AHEXAHEXBKMT2A
SCHEMBL8161030 1.00 STAT3 (0.55) STAT3HIF1AHEXAHEXBKMT2A
SCHEMBL8878406 1.00 STAT3 (0.55) STAT3HIF1AHEXAHEXBKMT2A
SCHEMBL21988079 0.99 STAT3 (0.56) STAT3HIF1AHEXAHEXBKMT2A
SCHEMBL7485132 0.90 STAT3 (0.65) STAT3HIF1AKMT2AMEN1POLB
SCHEMBL6263953 0.90 STAT3 (0.65) STAT3HIF1AKMT2AMEN1POLB
SCHEMBL18376159 0.90 STAT3 (0.65) STAT3HIF1AKMT2AMEN1POLB
SCHEMBL8071104 0.90 STAT3 (0.65) STAT3HIF1AKMT2AMEN1POLB
SCHEMBL418871 0.90 STAT3 (0.65) STAT3HIF1AKMT2AMEN1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7176255-B2 Method for producing aqueous polymer dispersions containing colorants BASF AKTIENGESELLSCHAFT (DE) 2007-02-13 US disclosed
US-20050075453-A1 Method for producing aqueous polymer dispersions containing colorants BASF AKTIENGESELLSCHAF (DE) 2005-04-07 US disclosed
US-6727318-B1 EMULSION POLYMERIZATION OF ETHYLENICALLY UNSATURATED AND DYE-COMPRISING MONOMERS IN PRESENCE OF FREE-RADICAL INITIATORS BASF AKTIENGESELLSCHAFT (DE) 2004-04-27 US disclosed