⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12424423 | 1.00 | — | — | |
| SCHEMBL1001559 | 0.79 | — | — | |
| SCHEMBL1066618 | 0.77 | — | — | |
| SCHEMBL1001553 | 0.74 | — | — | |
| SCHEMBL15999684 | 0.74 | — | — | |
| SCHEMBL19147974 | 0.74 | — | — | |
| SCHEMBL12214929 | 0.74 | — | — | |
| SCHEMBL11423545 | 0.74 | — | — | |
| SCHEMBL20836758 | 0.74 | — | — | |
| SCHEMBL15142570 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105377812-B | The preparation method of 2- amino -2- oximido-N- alkoxy acetimidoyl cyanides and its prepare intermediate | 组合化学工业株式会社 | 2018-09-18 | — | — | CN | disclosed |
| EP-3012247-B1 | MANUFACTURING METHOD FOR 2-AMINO-2-HYDROXYIMINO-N-ALKOXY ACETOIMIDOYL CYANIDE, AND MANUFACTURING INTERMEDIATE THEREOF | KUMIAI CHEMICAL INDUSTRY CO (JP) | 2018-01-10 | — | — | EP | disclosed |
| EP-3012247-A2 | MANUFACTURING METHOD FOR 2-AMINO-2-HYDROXYIMINO-N-ALKOXY ACETOIMIDOYL CYANIDE, AND MANUFACTURING INTERMEDIATE THEREOF | Ihara Chemical Industry Co., Ltd. (JP) | 2016-04-27 | — | — | EP | disclosed |
| CN-105377812-A | Manufacturing method for 2-amino-2-hydroxyimino-n-alkoxy acetoimidoyl cyanide, and manufacturing intermediate thereof | IHARA CHEMICAL IND CO | 2016-03-02 | — | — | CN | disclosed |
| CN-102659683-B | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2014-11-12 | — | — | CN | disclosed |
| EP-2366704-B1 | Inhibitors of serine proteases | VERTEX PHARMA (US) | 2013-10-23 | — | — | EP | disclosed |
| CN-101573319-B | Process for preparing 1-(2-ethyl-butyl)-cyclohexanecarboxylic acid | HOFFMANN LA ROCHE | 2013-04-03 | — | — | CN | disclosed |
| US-20120264711-A1 | ANTIVIRAL COMPOUNDS | GILEAD SCIENCES, INC. (US) | 2012-10-18 | — | — | US | disclosed |
| CN-102659683-A | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2012-09-12 | — | — | CN | disclosed |
| CN-101384556-B | Process for producing 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL IND CO | 2012-06-20 | — | — | CN | disclosed |
| EP-1990336-B1 | PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND | IHARA CHEMICAL IND CO (JP) | 2012-02-08 | — | — | EP | disclosed |
| US-7812175-B2 | Process for production of 5-alkoxy-4-hydroxymethylpyrazole compound | IHARA CHEMICAL INDUSTRY CO., LTD. (JP) | 2010-10-12 | — | — | US | disclosed |
| CN-101573319-A | Process for preparing 1- (2-ethyl-butyl) -cyclohexanecarboxylic acid | HOFFMANN LA ROCHE (CH) | 2009-11-04 | — | — | CN | disclosed |
| US-20090036688-A1 | Process for Production of 5-Alkoxy-4-Hydroxymethylpyrazole Compound | IHARA CHEMICAL INDUSTRY CO., LTD (JP) | 2009-02-05 | — | — | US | disclosed |
| EP-1990336-A1 | PROCESS FOR PRODUCTION OF 5-ALKOXY-4-HYDROXYMETHYLPYRAZOLE COMPOUND | Ihara Chemical Industry Co., Ltd. (JP) | 2008-11-12 | — | — | EP | disclosed |