SCHEMBL5375964

SCHEMBL5375964

CN(C)c1c(C(F)(F)F)c2ccccc2oc1=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 4/20 0.56
GLA P06280 2/20 0.44
CYP1A2 P05177 2/20 0.44
KDM4E B2RXH2 5/20 0.41
ALDH1A1 P00352 4/20 0.41
MAPT P10636 3/20 0.40
VKORC1 Q9BQB6 1/20 0.40
NQO1 P15559 1/20 0.40
POLB P06746 1/20 0.39
HPGD P15428 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
CYP3A4 P08684 2/20 0.39
PGAM1 P18669 1/20 0.39
MAOA P21397 1/20 0.39
CASP1 P29466 1/20 0.39
CASP7 P55210 1/20 0.39
HSD17B10 Q99714 1/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
KMT2A Q03164 3/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5375965 0.88 GAA (0.60) GAAGLACYP1A2KDM4EALDH1A1
SCHEMBL6745344 0.85 GAA (0.44) GAAGLACYP1A2KDM4EALDH1A1
SCHEMBL10701539 0.84 GAA (0.42) GAAGLACYP1A2KDM4EALDH1A1
SCHEMBL31457913 0.80 KDM4E (0.48) GAAGLACYP1A2KDM4EALDH1A1
SCHEMBL15842508 0.80 KDM4E (0.48) GAAGLACYP1A2KDM4EALDH1A1
SCHEMBL1660191 0.77 GAA (0.63) GAAGLACYP1A2KDM4EALDH1A1
SCHEMBL27950168 0.76 KDM4E (0.53) GAAGLACYP1A2KDM4EALDH1A1
SCHEMBL1095040 0.76 KDM4E (0.53) GAACYP1A2KDM4EALDH1A1MAPT
SCHEMBL557751 0.76 GAA (0.62) GAAKDM4EALDH1A1MAPTNQO1
SCHEMBL1823146 0.75 CA12 (0.52) GLACYP1A2KDM4EALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7234853-B2 Textile product with illuminated fibers manufacturing process LUMINEX S.P.A. (IT) 2007-06-26 US disclosed
EP-1740929-A1 AUTHENTICATION SYSTEM, DATA DEVICE, AND METHODS FOR USINGTHE SAME GENERAL ELECTRIC COMPANY (US) 2007-01-10 EP disclosed
EP-1690235-A2 METHOD OF AUTHENTICATING POLYMERS, AUTHENTICATABLE POLYMERS, METHODS OF MAKING AUTHENTICATABLE POLYMERS AND AUTHENTICATABLE ARTICLES, AND ARTICLES MADE THERE FROM GENERAL ELECTRIC COMPANY (US) 2006-08-16 EP disclosed
EP-1307687-B1 TEXTILE PRODUCT WITH ILLUMINATED FIBRES, ARTICLE MADE THEREFROM AND PRODUCTION METHOD OF THE SAME LUMINEX S P A (IT) 2006-03-08 EP disclosed
WO-2005106434-A1 AUTHENTICATION SYSTEM, DATA DEVICE, AND METHODS FOR USINGTHE SAME GENERAL ELECTRIC COMPANY (US) 2005-11-10 WO disclosed
WO-2005055156-A2 METHOD OF AUTHENTICATING POLYMERS, AUTHENTICATABLE POLYMERS, METHODS OF MAKING AUTHENTICATABLE POLYMERS AND AUTHENTICATABLE ARTICLES, AND ARTICLES MADE THERE FROM GENERAL ELECTRIC COMPANY (US) 2005-06-16 WO disclosed
US-20030156426-A1 Textile product with illuminated fibres, article made therefrom and production method of the same LUMINEX S.P.A. (IT) 2003-08-21 US disclosed
EP-0276016-A2 Photopolymerizable composition Nippon Paint Co., Ltd. (JP) 1988-07-27 EP disclosed