⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8124733 | 0.96 | TRIM24 (0.41) | — | |
| SCHEMBL771545 | 0.87 | — | — | |
| SCHEMBL595135 | 0.79 | — | — | |
| SCHEMBL7981543 | 0.73 | — | — | |
| SCHEMBL119955 | 0.73 | — | — | |
| SCHEMBL3118747 | 0.69 | — | — | |
| SCHEMBL7645220 | 0.69 | TRIM24 (0.64) | — | |
| SCHEMBL3115436 | 0.69 | — | — | |
| SCHEMBL8036939 | 0.69 | TRIM24 (0.64) | — | |
| Water SCHEMBL10380917 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 25609 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4392415-A1 | SUBSTITUTED AMINOPYRIDINE COMPOUNDS AS EGFR INHIBITORS | Yuhan Corporation (KR) | 2024-07-03 | — | — | EP | claimed |
| WO-2024137358-A1 | KDM1A INHIBITORS FOR THE TREATMENT OF DISEASE | IMAGO BIOSCIENCES, INC. (US) | 2024-06-27 | — | — | WO | claimed |
| US-11981658-B2 | Substituted aminopyridine compounds as EGFR inhibitors | YUHAN CORPORATION (KR) | 2024-05-14 | — | — | US | claimed |
| WO-2024094170-A1 | INHIBITOR OF UBIQUITIN-SPECIFIC PROTEASE 1 AND USE THEREOF | 深圳晶泰科技有限公司 | 2024-05-10 | — | — | WO | claimed |
| CN-117980297-A | Substituted aminopyridine compounds as EGFR inhibitors | 柳韩洋行 | 2024-05-03 | — | — | CN | claimed |
| US-20240018140-A1 | MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2024-01-18 | — | — | US | claimed |
| WO-2023245015-A2 | PHENYL AMIDE COMPOUNDS AND METHODS OF USE | SCHRÖDINGER, INC. (US) | 2023-12-21 | — | — | WO | claimed |
| EP-4213843-A2 | MODIFIED IMIDAZOPYRIDINES AS GLUCOSYLCERAMIDE SYNTHASE INHIBITORS | Merck Sharp & Dohme LLC (US) | 2023-07-26 | — | — | EP | claimed |
| WO-2023060362-A1 | RAS INHIBITORS, COMPOSITIONS AND METHODS OF USE THEREOF | GENETOLEAD INC. (CA) | 2023-04-20 | — | — | WO | claimed |
| WO-2023049060-A1 | ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTORS | MERCK SHARP & DOHME LLC (US) | 2023-03-30 | — | — | WO | claimed |
| US-4749705-A | Quinazoline derivative and anti-hypertensive agents | KOTOBUKI SEIYAKU CO., LTD. (JP) | 1988-06-07 | — | — | US | claimed |
| EP-0266950-A2 | Nor-statine and nor-cyclostatine polypeptides | PFIZER INC. (US) | 1988-05-11 | — | — | EP | claimed |
| US-4735959-A | HYPOGLYCEMIC AGENTS | DR. KARL THOMAE GMBH (DE) | 1988-04-05 | — | — | US | claimed |
| EP-0254737-A1 | FUSED BENZAZEPINES. | SCHERING CORP (US) | 1988-02-03 | — | — | EP | claimed |
| US-4711890-A | TREATMENT OF ANXIETY STATES OR OF PULMONARY, RENAL, CIRCULATORY OF CARDIOVASCULAR DISORDERS | RHONE-POULENC SANTE (FR) | 1987-12-08 | — | — | US | claimed |
| US-4684652-A | TREATING ANXIETY OR CARDIOVASCULAR DISORDERS | RHONE-POULENC SANTE (FR) | 1987-08-04 | — | — | US | claimed |
| WO-1987004430-A2 | FUSED BENZAZEPINES | SCHERING CORPORATION (US) | 1987-07-30 | — | — | WO | claimed |
| EP-0230270-A2 | Fused benzazepines | SCHERING CORPORATION (US) | 1987-07-29 | — | — | EP | claimed |
| EP-0112776-B1 | MEDICAMENTS BASED ON NAPHTHALENE OR AZANAPHTHALENE CARBOXAMIDES, NAPHTALENE OR AZANAPHTHALENE CARBOXAMIDE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION | RHONE-POULENC SANTE (FR) | 1987-07-22 | — | — | EP | claimed |
| EP-0005299-A1 | Substituted 1-phenyl-2,3,4,5-tetrahydro-1H-3-benzazepines, process for the preparation thereof, and pharmaceutical compositions containing them | Technobiotic Ltd. (CH) | 1979-11-14 | — | — | EP | claimed |