SCHEMBL537655

SCHEMBL537655

CC(C)(C)c1cc(Cc2cc(C(C)(C)C)cc(C(C)(C)C)c2OP(=O)(O)O)c(O)c(C(C)(C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSPA5 P11021 2/20 0.45
CYP2C19 P33261 4/20 0.44
CYP2C9 P11712 3/20 0.44
HIF1A Q16665 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
CYP2D6 P10635 1/20 0.40
HSD17B10 Q99714 1/20 0.40
GAA P10253 2/20 0.38
ALDH1A1 P00352 1/20 0.38
XBP1 P17861 1/20 0.38
MAPK1 P28482 1/20 0.38
HTT P42858 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
NR5A2 O00482 1/20 0.38
NR5A1 Q13285 1/20 0.38
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
HMGCR P04035 3/20 0.34
NR1I2 O75469 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2329462 0.99 HSPA5 (0.44) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL2678093 0.99 HSPA5 (0.44) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL2334329 0.93 INPPL1 (0.36) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL29612109 0.93 INPPL1 (0.36) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL20299533 0.92 INPPL1 (0.35) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL20299525 0.92 INPPL1 (0.35) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL20299554 0.92 INPPL1 (0.35) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL35073 0.92 INPPL1 (0.35) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL9660044 0.92 INPPL1 (0.35) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2
SCHEMBL1132177 0.92 INPPL1 (0.35) HSPA5CYP2C19CYP2C9HIF1ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1694368-B1 TERMINAL STERILIZATION OF PREFILLED CONTAINERS BECTON DICKINSON CO (US) 2012-02-08 EP claimed
US-8003725-B2 Plasticized hetero-phase polyolefin blends EXXONMOBIL CHEMICAL PATENTS INC. (US) 2011-08-23 US claimed
EP-2308516-A1 Terminal sterilization of prefilled containers Becton Dickinson and Company (US) 2011-04-13 EP claimed
EP-2305317-A1 Terminal sterilization of prefilled containers Becton Dickinson and Company (US) 2011-04-06 EP claimed
EP-2013282-B1 ARTICLES FROM PLASTICIZED THERMOPLASTIC POLYLEFIN COMPOSITIONS EXXONMOBIL CHEM PATENTS INC (US) 2010-01-20 EP claimed
EP-2013282-A1 ARTICLES FROM PLASTICIZED THERMOPLASTIC POLYLEFIN COMPOSITIONS ExxonMobil Chemical Patents Inc. (US) 2009-01-14 EP claimed
US-20090012466-A1 Terminal Sterilization of Prefilled Containers BECTON, DICKINSON AND COMPANY (US) 2009-01-08 US claimed
US-20080045638-A1 Plasticized hetero-phase polyolefin blends EXXONMOBIL CHEMICAL PATENTS INC. 2008-02-21 US claimed
EP-1694368-A4 TERMINAL STERILIZATION OF PREFILLED CONTAINERS BECTON DICKINSON CO (US) 2007-11-07 EP claimed
WO-2007120147-A1 ARTICLES FROM PLASTICIZED THERMOPLASTIC POLYLEFIN COMPOSITIONS EXXONMOBIL CHEMICAL PATENTS INC. (US) 2007-10-25 WO claimed
EP-1694368-A2 TERMINAL STERILIZATION OF PREFILLED CONTAINERS Becton, Dickinson and Company (US) 2006-08-30 EP claimed
WO-2005058377-A2 TERMINAL STERILIZATION OF PREFILLED CONTAINERS BECTON, DICKINSON AND COMPANY (US) 2005-06-30 WO claimed
US-20050129569-A1 Terminal sterilization of prefilled containers BECTON, DICKINSON AND COMPANY 2005-06-16 US claimed
EP-1879953-B1 POLYPROPYLENE BASED FIBERS AND NONWOVENS EXXONMOBIL CHEMICAL PATENTS INC (US) 2018-09-19 EP disclosed
EP-2953986-A1 INCIPIENT WETNESS METHOD TO ENHANCE PRODUCTIVITY OF SUPPORTED ZIEGLER-NATTA CATALYSTS ExxonMobil Chemical Patents Inc. (US) 2015-12-16 EP disclosed
US-9018209-B2 Compounds and methods for the treatment of viruses and cancer YALE UNIVERSITY (US) 2015-04-28 US disclosed
US-20060189744-A1 Articles from plasticized thermoplastic polyolefin compositions EXXONMOBIL CHEMICAL PATENTS, INC. 2006-08-24 US disclosed
WO-2005058377-A2 TERMINAL STERILIZATION OF PREFILLED CONTAINERS BECTON, DICKINSON AND COMPANY (US) 2005-06-30 WO disclosed
US-20050129569-A1 Terminal sterilization of prefilled containers BECTON, DICKINSON AND COMPANY 2005-06-16 US disclosed
US-20050113517-A1 Propylene-ethylene random block copolymer and biaxially oriented multi-layer film using the same as a surface layer JAPAN POLYPROPYLENE CORPORATION (JP) 2005-05-26 US disclosed