Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | GSK3B | P49841 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.43 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377143 | 0.95 | MEN1 (0.49) | PTGDR2SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5397126 | 0.89 | GAA (0.61) | PTGDR2SMN1; SMN2MEN1KMT2ANR1H4 | |
| SCHEMBL6593163 | 0.88 | GAA (0.58) | PTGDR2SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL6593156 | 0.88 | GAA (0.58) | PTGDR2SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5380788 | 0.88 | FFAR1 (0.52) | — | |
| SCHEMBL5381942 | 0.85 | SMN1; SMN2 (0.58) | PTGDR2SMN1; SMN2MEN1KMT2AGAA | |
| SCHEMBL5372013 | 0.82 | FFAR1 (0.39) | SMN1; SMN2KMT2ALMNAALDH1A1 | |
| SCHEMBL5407247 | 0.82 | GAA (0.64) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL5407245 | 0.82 | GAA (0.64) | SMN1; SMN2MEN1KMT2AGAALMNA | |
| SCHEMBL5372048 | 0.81 | MEN1 (0.51) | PTGDR2MEN1KMT2ANR1H4L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7179823-B1 | 5-membered n-heterocyclic compounds with hypoglycemic and hypolipidemic activity | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-02-20 | — | — | US | disclosed |