SCHEMBL5377

SCHEMBL5377

CC1C[N]CC(C)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2914215 0.80
SCHEMBL3488092 0.68
SCHEMBL596776 0.68
SCHEMBL92614 0.68
SCHEMBL24269492 0.68
SCHEMBL25101528 0.68
SCHEMBL10273860 0.68
SCHEMBL2043699 0.67
SCHEMBL477065 0.65
SCHEMBL477089 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 713 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112469715-B Pyrimidine compound and pharmaceutical composition for preventing or treating cancer comprising the same 韩美药品株式会社 2024-06-11 CN claimed
CN-118019736-A Molecular gel compound designed based on cereblon protein and application thereof 标新生物医药科技(上海)有限公司 2024-05-10 CN claimed
WO-2024051766-A1 MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF 标新生物医药科技(上海)有限公司 2024-03-14 WO claimed
EP-3921319-B1 IMIDAZO [2, 1-F] [1, 2, 4] TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEIGENE LTD (KY) 2024-03-06 EP claimed
CN-116284001-A DCLK1 inhibitor, preparation method, pharmaceutical composition and application 中国药科大学 2023-06-23 CN claimed
US-20230167117-A1 IMIDAZO[2,1-F][1,2,4]TRIAZIN-4-AMINE DERIVATIVES AS TLR7 AGONIST BEONE MEDICINES I GMBH (CH) 2023-06-01 US claimed
CN-111606883-B Sulfur-containing compound based on glutarimide skeleton and application thereof 上海科技大学 2023-05-09 CN claimed
US-20220143002-A1 SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF SHANGHAITECH UNIVERSITY (CN) 2022-05-12 US claimed
CN-112402385-B 4-hydroxymethyl-1H-indole compound pharmaceutical preparation and preparation method thereof 北京华氏开元医药科技有限公司 2022-04-01 CN claimed
EP-3932922-A1 SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF ShanghaiTech University (CN) 2022-01-05 EP claimed
WO-1994010142-A1 NEW SUBSTITUTED AZETIDINONES AS ANTI-INFLAMMATORY AND ANTIDEGENERATIVE AGENTS MERCK & CO., INC. (US) 1994-05-11 WO claimed
EP-0447484-A1 ANTIBACTERIAL QUINOLONE COMPOUNDS THE UPJOHN COMPANY (US) 1991-09-25 EP claimed
EP-0305492-A4 PHOSPHOLIPASE A 2? INHIBITORS 1991-09-04 EP claimed
US-4971967-A Quinolinecarboxylic acid derivatives, antibacterial compositions and use KANEBO LTD (JP) 1990-11-20 US claimed
EP-0160284-B1 QUINO-BENOXAZINE ANTIBACTERIAL COMPOUNDS ABBOTT LABORATORIES (US) 1990-10-24 EP claimed
EP-0387877-A1 Quinolinecarboxylic acid derivatives and antibacterial agent containing the same KANEBO LTD. (JP) 1990-09-19 EP claimed
WO-1990006307-A2 ANTIBACTERIAL QUINOLONE COMPOUNDS THE UPJOHN COMPANY (US) 1990-06-14 WO claimed
EP-0305492-A1 PHOSPHOLIPASE A 2? INHIBITORS AMERICAN HOME PRODUCTS CORPORATION (US) 1989-03-08 EP claimed
US-4792555-A DESENSITIZERS; ANTIINFLAMMATORY AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1988-12-20 US claimed
WO-1988006885-A1 PHOSPHOLIPASE A2 INHIBITORS AMERICAN HOME PRODUCTS CORPORATION (US) 1988-09-22 WO claimed