Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5337107 | 0.91 | IKBKB (0.60) | IKBKBCHUK | |
| SCHEMBL5333199 | 0.88 | IKBKB (0.59) | IKBKBCHUK | |
| SCHEMBL5334295 | 0.87 | IKBKB (0.74) | IKBKBCHUK | |
| SCHEMBL5339604 | 0.86 | IKBKB (0.55) | IKBKBCHUK | |
| SCHEMBL5334175 | 0.85 | IKBKB (0.69) | IKBKBCHUK | |
| SCHEMBL5340714 | 0.84 | IKBKB (0.73) | IKBKBCHUK | |
| SCHEMBL14558812 | 0.82 | IKBKB (0.60) | IKBKBCHUK | |
| SCHEMBL5335615 | 0.82 | IKBKB (0.58) | IKBKBCHUK | |
| SCHEMBL14558192 | 0.82 | IKBKB (0.60) | IKBKBCHUK | |
| Hydrochloric Acid SCHEMBL5333316 | 0.82 | IKBKB (0.60) | IKBKBCHUK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7186743-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186743-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-7186743-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2007-03-06 | — | — | US | disclosed |
| US-6956052-B2 | Substituted pyrazolyl compounds for the treatment of inflammation | PHARMACIA CORPORATION (US) | 2005-10-18 | — | — | US | disclosed |