Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APOBEC3A | P31941 | 1/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 6/20 | 0.33 |
| ▸ | AURKA | O14965 | 1/20 | 0.32 |
| ▸ | DAPK3 | O43293 | 1/20 | 0.32 |
| ▸ | JAK2 | O60674 | 1/20 | 0.32 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.32 |
| ▸ | ABL1 | P00519 | 1/20 | 0.32 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | RET | P07949 | 1/20 | 0.32 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.32 |
| ▸ | PRKACA | P17612 | 1/20 | 0.32 |
| ▸ | KDR | P35968 | 1/20 | 0.32 |
| ▸ | MAP2K2 | P36507 | 1/20 | 0.32 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.32 |
| ▸ | CDK8 | P49336 | 1/20 | 0.32 |
| ▸ | GSK3A | P49840 | 1/20 | 0.32 |
| ▸ | GSK3B | P49841 | 1/20 | 0.32 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5377933 | 1.00 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| SCHEMBL4148693 | 0.87 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| SCHEMBL4148687 | 0.87 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| Ammonia Solution, Strong SCHEMBL4153549 | 0.86 | APOBEC3A (0.34) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| Ammonia Solution, Strong SCHEMBL4153546 | 0.86 | APOBEC3A (0.34) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| SCHEMBL13852252 | 0.84 | APOBEC3A (0.32) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| SCHEMBL4155376 | 0.83 | SYK (0.32) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| SCHEMBL4155381 | 0.83 | SYK (0.32) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| SCHEMBL5599054 | 0.83 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYKAURKADAPK3 | |
| SCHEMBL5599047 | 0.83 | APOBEC3A (0.35) | APOBEC3AAPOBEC3GSYKAURKADAPK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007088148-A1 | DERIVATIVES OF THIOPHENE CARBOXILIC ACID AS ANTIVIRAL AGENT | SMITHKLINE BEECHAM CORPORATION (US) | 2007-08-09 | — | — | WO | disclosed |