Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.59 |
| ▸ | CTSD | P07339 | 11/20 | 0.56 |
| ▸ | BACE1 | P56817 | 12/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5371267 | 0.82 | BACE1 (0.55) | BCHECTSDBACE1 | |
| SCHEMBL5578298 | 0.82 | BCHE (0.51) | BCHECTSDBACE1 | |
| SCHEMBL6704614 | 0.80 | BACE1 (0.59) | BCHECTSDBACE1 | |
| SCHEMBL6702679 | 0.80 | BACE1 (0.59) | BCHECTSDBACE1 | |
| SCHEMBL3354218 | 0.79 | BCHE (0.77) | BCHECTSDBACE1 | |
| SCHEMBL3510079 | 0.79 | BCHE (0.77) | BCHECTSDBACE1 | |
| SCHEMBL3354210 | 0.79 | BCHE (0.77) | BCHECTSDBACE1 | |
| SCHEMBL6896962 | 0.79 | BCHE (0.77) | BCHECTSDBACE1 | |
| SCHEMBL3508050 | 0.79 | BACE1 (0.59) | BCHECTSDBACE1 | |
| SCHEMBL3356216 | 0.79 | BCHE (0.50) | BCHECTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |