Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.66 |
| ▸ | CTSD | P07339 | 3/20 | 0.66 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.63 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13307099 | 1.00 | BACE1 (0.66) | BACE1CTSDBACE2 | |
| SCHEMBL13307041 | 0.94 | BACE1 (0.67) | BACE1CTSDBACE2 | |
| SCHEMBL5383584 | 0.94 | BACE1 (0.67) | BACE1CTSDBACE2 | |
| SCHEMBL3350715 | 0.93 | BACE1 (0.76) | BACE1CTSDBACE2 | |
| SCHEMBL5374592 | 0.92 | BACE1 (0.65) | BACE1CTSDBACE2 | |
| SCHEMBL3349699 | 0.92 | BACE1 (0.70) | BACE1CTSDBACE2 | |
| SCHEMBL3355280 | 0.92 | BACE1 (0.72) | BACE1CTSDBACE2 | |
| SCHEMBL5378246 | 0.92 | BACE1 (0.65) | BACE1CTSDBACE2 | |
| SCHEMBL13306988 | 0.92 | BACE1 (0.65) | BACE1CTSDBACE2 | |
| SCHEMBL13307589 | 0.90 | BACE1 (0.65) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176242-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2007-02-13 | — | — | US | disclosed |