Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGLN1 | Q9GZT9 | 7/20 | 0.53 |
| ▸ | BBOX1 | O75936 | 5/20 | 0.53 |
| ▸ | FTO | Q9C0B1 | 4/20 | 0.53 |
| ▸ | THRA | P10827 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL523061 | 0.77 | EGLN1 (0.60) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL523708 | 0.74 | EGLN1 (0.58) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL5379776 | 0.74 | EGLN1 (0.46) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522787 | 0.72 | EGLN1 (0.65) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL29390250 | 0.70 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL522744 | 0.70 | EGLN1 (1.00) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL30580347 | 0.69 | TDP1 (0.56) | TDP1 | |
| SCHEMBL129880 | 0.69 | TDP1 (0.56) | TDP1 | |
| SCHEMBL2015310 | 0.68 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB | |
| SCHEMBL27773936 | 0.68 | EGLN1 (0.59) | EGLN1BBOX1FTOTHRATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007047194-A2 | METHODS FOR TREATING MITF-RELATED DISORDERS | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2007-04-26 | — | — | WO | disclosed |